Protein Info for Atu1686 in Agrobacterium fabrum C58

Annotation: peptidyl-prolyl cis-trans isomerse D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 163 (163 residues), 127.4 bits, see alignment E=9.6e-41 PF13623: SurA_N_2" amino acids 2 to 138 (137 residues), 73.7 bits, see alignment E=2.9e-24 PF13145: Rotamase_2" amino acids 247 to 369 (123 residues), 96.5 bits, see alignment E=3.9e-31

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 100% identity to atu:Atu1686)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CIS0 at UniProt or InterPro

Protein Sequence (630 amino acids)

>Atu1686 peptidyl-prolyl cis-trans isomerse D (Agrobacterium fabrum C58)
MLDSLRNASRTMAAKLLLLLLVVSFGVWGVSASLVTANSHAVMTVGDQTVSPQEFRLAYQ
RQVSDLSRQFGTRLTTEQAKAFGIDRQVFSQLAAGAALDELASKMNLGLSENRLANLIAE
DPAFKSVNGQFDRNLFSERLRNSGFREDDYIKERSKVAVRSQIVEAVSDGFAAPQVLVDA
LKQYRNEQRAVDYVILSNAVIPPVKAPGDDVLTPWFETNKSKYRAPEFRKFTYVKLEPSD
IAEPASVTDAQIADYYNSHKDSFRTAGRRTVEQLTFPDKEMAAAAAEQIRLGNTTYDQVV
KDQGKTASDVTLGEFTKDTIPDQSIADAAFAIQKDGGVSPVVDGSFGPILLRVTGIKPET
TRTLDEAKEDIRKDLATAAAAEEITNVHDRYEDLRAGGSSLADAAKQLNLKPVTIDAIDA
AGLNEKGDAIEGLPSPQLAQDVFKTEPGTDALPINLGREGYIWFDVEQIIPARDRTLAEV
RDDVVADWTAEQQRTALAAKADELKARVEKGETLEAVAGELSLAVEQKSGLRRTSEDAIF
GRQTIAAVFSGAEGVVGTAADADGSSRILFKVTSVDANAPADALANDDQQFTAIARAAGD
DMLDQMVNRLQNDYGVTINQALADQAMVGF