Protein Info for Atu1519 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein (zinc)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 43 to 74 (32 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 171 to 201 (31 residues), see Phobius details amino acids 213 to 234 (22 residues), see Phobius details amino acids 242 to 262 (21 residues), see Phobius details PF00950: ABC-3" amino acids 4 to 257 (254 residues), 242.9 bits, see alignment E=2.1e-76

Best Hits

Swiss-Prot: 53% identical to ZNUB_ECOLI: High-affinity zinc uptake system membrane protein ZnuB (znuB) from Escherichia coli (strain K12)

KEGG orthology group: K09816, zinc transport system permease protein (inferred from 100% identity to atu:Atu1519)

MetaCyc: 53% identical to Zn2+ ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]

Predicted SEED Role

"Zinc ABC transporter, inner membrane permease protein ZnuB" in subsystem Transport of Zinc

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZ27 at UniProt or InterPro

Protein Sequence (272 amino acids)

>Atu1519 ABC transporter, membrane spanning protein (zinc) (Agrobacterium fabrum C58)
MFDDFFVRAMVAGIGVALTAGPLGCFVVWRRMAYFGDTMAHSALLGVALSLLLQLNLIVS
VFLVASAVSILLIFLQRRQALSSDALLGILSHSALAIGLVIVAFMSWVRIDLVSFLFGDI
LAVTRSDIALIWGGGLVVIVSMVFLWRSLLASTVNTELAEAEGLNPERSKLIFTLLMALV
IAIAMKVVGIMLITSLLIIPAATARRFSSTPEVMAVVASLIGAVAVVGGLFGSLTYDTPS
GPSIVVAAVILFVISLLPAPGFSRSADEGGKP