Protein Info for Atu1505 in Agrobacterium fabrum C58

Annotation: penicillin-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 signal peptide" amino acids 1 to 49 (49 residues), see Phobius details PF00768: Peptidase_S11" amino acids 53 to 270 (218 residues), 190.1 bits, see alignment E=7e-60 PF13354: Beta-lactamase2" amino acids 58 to 201 (144 residues), 43.6 bits, see alignment E=3.3e-15 PF05036: SPOR" amino acids 418 to 496 (79 residues), 48.1 bits, see alignment E=1.8e-16

Best Hits

KEGG orthology group: K01286, D-alanyl-D-alanine carboxypeptidase [EC: 3.4.16.4] (inferred from 100% identity to atu:Atu1505)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZ39 at UniProt or InterPro

Protein Sequence (499 amino acids)

>Atu1505 penicillin-binding protein (Agrobacterium fabrum C58)
MRLKSSAVLKSLSGAHSRKAGATSFVRFVALTLAAAFIAATSVQTAKADPKYAGIVIDAK
SGKVLYGEDPDGLRYPASLTKMMTLYLTFEALNSGRISLDSRVTVSANAAKEPPSKLGVR
AGGSVTVEQAILALVTRSANDMATALGEHLGGSEDRFARMMTAKARALGMTRTTYRNANG
LPNTAQMTTARDQARLGIALRQHFPQYYGYFSTRTFNFGKQVIGNHNRLVGTVKGVDGIK
TGYTRAAGSNLATSAQLDGRSIVAVVLGGRSSAARDATMRKLVATYLPQASRGGNSNLIA
QTRSGPVEEPVTVAAAAPYPSVAVAATDSGLPNAGPVPQTRYEEAPVTAFAGSSSNAAVK
AMEAATWQKGKDPIVRAPVAPDRKLITNSTKVDNIVTASTAASASAAPSVSPRAEAPQGG
WVIQIGASPDENSARGLLQNAQEKGGAALRSAKPFTVAFSKDGSQIYRARFGGFDGQNAA
VNACNVLKKKGVSCWASLQ