Protein Info for Atu1416 in Agrobacterium fabrum C58

Annotation: long-chain-fatty-acid-CoA-ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 PF00501: AMP-binding" amino acids 41 to 420 (380 residues), 141.5 bits, see alignment E=3.3e-45 PF23562: AMP-binding_C_3" amino acids 476 to 598 (123 residues), 23.3 bits, see alignment E=7.4e-09

Best Hits

KEGG orthology group: K12508, feruloyl-CoA synthase [EC: 6.2.1.34] (inferred from 100% identity to atu:Atu1416)

Predicted SEED Role

"Trans-feruloyl-CoA synthase (EC 6.2.1.34)" (EC 6.2.1.34)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.2.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZA8 at UniProt or InterPro

Protein Sequence (611 amino acids)

>Atu1416 long-chain-fatty-acid-CoA-ligase (Agrobacterium fabrum C58)
MSVKLWSPDVAWEKRPNGEIMIWRNDPLGPYPQKLNERLLHWCRSAPERTWMADRQGREP
WRRVSYAEALDKIRRIGQFLLDHDLSVERPLLVLSENSIEHALMVLAAQHVGIASAAITP
AYATSADLTKLADIRGQITPGMVFAEDATPFRRALGEVFDDGTPLVGLRNLPEDRSNTFH
FETLLETEPTEAVDRAFDAVGPDTVAKFLFTSGTTGSPKAVIQTQRMLCSNQEMIADCYG
YFREEPPVVVDWAPWNHTAAGNKVFNLVLYNGGTYYIDRGKPSPAQIGQTLDNLRDISPT
WYFNVPAGHEMLVQAMRKDEALCRSFFRDLKMLMYAGAGMAQHTWDALTELSMATVGHAV
LMGAGLGSTETAPFSLFCTEPQDKPGNIGIPAQGVTMKLVPFDGRYELRLKGPNITPGYW
RNGELTAAAFDEEGFYRIGDTVKFAVADDPRRGFYFDGRMAENFKLQTGTWVAVGPLRAQ
LVNMFAGLIRDAVITGENRAELGALVVPFIPALRELVRGSQHLSDAEIIRHPSVRAQIVA
KLSAHQKQASGSASRVMRILVMEDALRFEKGEVTDKGSINQRAVLLHRKELVESLYGDTP
QVITVGREVAA