Protein Info for Atu1391 in Agrobacterium fabrum C58
Annotation: ABC transporter, nucleotide binding/ATPase protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 54% identical to GLNQ_GEOSE: Glutamine transport ATP-binding protein GlnQ (glnQ) from Geobacillus stearothermophilus
KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 100% identity to atu:Atu1391)MetaCyc: 52% identical to L-glutamine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]
Predicted SEED Role
"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.21
Use Curated BLAST to search for 3.6.3.21 or 7.4.2.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A9CJ54 at UniProt or InterPro
Protein Sequence (244 amino acids)
>Atu1391 ABC transporter, nucleotide binding/ATPase protein (Agrobacterium fabrum C58) MSLIEITEVRKSYGSNEVLKGINLDVEPGEVIAIIGKSGSGKSTLLRCINGLETISAGSI SVAGAQLLDDDLHLKALRLKVGMIFQQFNLFPHQTVGGNVMLSQTVVKKTPKPEAEAVAR TMLERVGLAHKFDAYPDELSGGQQQRVAIARALAMQPIALLCDEITSALDPELVSEVLAV VRELAGEGMTLLMVTHEMKFARDVCSRVVFMHEGRVHEIGPPEEVFSNPATPELKQFLGV AARH