Protein Info for Atu1339 in Agrobacterium fabrum C58

Annotation: ribonuclease E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 977 TIGR00757: ribonuclease, Rne/Rng family" amino acids 14 to 604 (591 residues), 510.5 bits, see alignment E=1.7e-157 PF10150: RNase_E_G" amino acids 300 to 570 (271 residues), 340.3 bits, see alignment E=8.7e-106 PF20833: RNase_E_G_Thio" amino acids 582 to 666 (85 residues), 97.4 bits, see alignment E=4.5e-32

Best Hits

KEGG orthology group: K08300, ribonuclease E [EC: 3.1.26.12] (inferred from 96% identity to atu:Atu1339)

Predicted SEED Role

"Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-)" in subsystem Bacterial Cell Division or RNA processing and degradation, bacterial (EC 3.1.4.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12 or 3.1.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CZH1 at UniProt or InterPro

Protein Sequence (977 amino acids)

>Atu1339 ribonuclease E (Agrobacterium fabrum C58)
MADKMLIDASHEEETRVVVVRGNRIEEFDFESEHKKQIRGNIYLAKVTRVEPSLQAAFVD
YGGNRHGFLAFAEIHPDYYQIPLADRQALLKAEAEDHRRSDDFESADAPESGAPMIDLSQ
VDQPDVGIVAASETTDVAVTEEVAPVSEAVSEETAVEVVAEEAPAEEEKPKKRVRRPRAK
KKTAEEIAAEAAEASSEDDGSTGGDMAAMVDTDTISEEVEGLRRGNDDDDDDDDDDHHEK
EVIESVGAEDAMEEVPDRVARKPRKQYRIQEVIKRRQILLVQVAKEERGNKGAALTTYLS
LAGRYSVLMPNTARGGGISRKITQPTDRKRLKEIARDLEVPQGMGVILRTAGANRTRVEI
KRDFEYLMRLWENVRTLTLNSTAPCLVYEEGSLIKRSIRDLYNKDISEIIVSGEEGYREA
KDFMKMLMPSHAKVVQPYRDIHPIFSRSGIEAQLDRMLQPQVTLKSGGYLIINQTEALVA
IDVNSGRSTREHSIEETALTTNLEAAEEVARQLRLRDLAGLVVIDFIDMEEKRNNRSVEK
KLKDCLKNDRARIQVGRISHFGLLEMSRQRIRASVLESTTQVCQHCGGTGHVRSESSIAL
HVLRGVEEYLLRNTTHNITVRCTPETALYLLNHKRGSIVDYEGRFGVAIIIAADSSVGAQ
HFAIDRGEAVENPVKIESLIQMLPSFVEEEDDIVIEVEEDEEEEEIVKAESAQPRQQPQG
DNGEDGKRKRKRRRRRRGKGGQNEQNGALDGQSGNDAEDDDAEGDDDGVETDEAGADSDE
NGANEAANADEDGKRKRRRRGKRGGRRNRDDALDAAGADGETEGEGAEGEEVSTAAPVTE
EPATAAEVVEGVVADVVAEEAPKKPRRTRKAKTKTETETEEAPKAETVETVEPVIIEPVV
VEATVVDVAIEEVGEASAGLAPGADVPGTEEKTRANRGSNVSSSEPVVTSSGSPASNPDG
DEPKPRKGGWWQRKGFF