Protein Info for Atu1217 in Agrobacterium fabrum C58

Annotation: cysteine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00291: PALP
  • amino acids 9 to 306 (298 residues), 236.7 bits, E=1.9e-74

Best Hits

KEGG orthology group: K01738, cysteine synthase A [EC: 2.5.1.47] (inferred from 100% identity to atu:Atu1217)

Predicted SEED Role

"Cysteine synthase B (EC 2.5.1.47)" in subsystem Cysteine Biosynthesis (EC 2.5.1.47)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• L-cysteine biosynthesis I (2/2 steps found)
• seleno-amino acid biosynthesis (plants) (3/5 steps found)
• superpathway of seleno-compound metabolism (8/19 steps found)

KEGG Metabolic Maps

• Cysteine metabolism
• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.47

Use Curated BLAST to search for 2.5.1.47

Sequence Analysis Tools

See A9CJD0 at UniProt or InterPro

Protein Sequence (345 amino acids)

>Atu1217 cysteine synthase (Agrobacterium fabrum C58)
MTIHSSALSAIGNTPLIRLKAASEATGCEILGKAEFLNPGQSVKDRAALYIIRDAERRGQ
LRPGGTIVEGTAGNTGIGLSLVANALGYKTVIVIPETQSQEKKDALKLLGAKLVEVPAAP
YSNPNNYVKVSGRLAKQLAATDENGAIWANQFDNIANRQAHIETTAPEIWDQTDGKVDGF
ICSVGSGGTLAGVADGLRDFNPDIKIGLADPEGAALYEFYKHGVLKSEGSSITEGIGQGR
ITANLEGFAPDFSYRISDAEALPVLFDLVTKEGLCLGGSSGINIAGAIRLARELGPGHTI
VTILCDYGNRYQSKLFNPDFLRSKGLPVPQWLATKSEIPVPYETV