Protein Info for Atu1077 in Agrobacterium fabrum C58

Annotation: DNA repair protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 TIGR00416: DNA repair protein RadA" amino acids 1 to 431 (431 residues), 544 bits, see alignment E=1.3e-167 PF18073: Zn_ribbon_LapB" amino acids 8 to 35 (28 residues), 39 bits, see alignment (E = 2.6e-13) PF00154: RecA" amino acids 68 to 201 (134 residues), 28.5 bits, see alignment E=5.2e-10 PF06745: ATPase" amino acids 71 to 142 (72 residues), 48.8 bits, see alignment E=3.1e-16 PF13481: AAA_25" amino acids 78 to 222 (145 residues), 65.4 bits, see alignment E=2.8e-21 PF00004: AAA" amino acids 92 to 193 (102 residues), 25.2 bits, see alignment E=9.9e-09 PF13541: ChlI" amino acids 343 to 427 (85 residues), 30.6 bits, see alignment E=1.4e-10 PF05362: Lon_C" amino acids 363 to 428 (66 residues), 22.3 bits, see alignment E=4.5e-08

Best Hits

Swiss-Prot: 79% identical to RADA_BRUA2: DNA repair protein RadA (radA) from Brucella abortus (strain 2308)

KEGG orthology group: K04485, DNA repair protein RadA/Sms (inferred from 100% identity to atu:Atu1077)

Predicted SEED Role

"DNA repair protein RadA" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJI4 at UniProt or InterPro

Protein Sequence (468 amino acids)

>Atu1077 DNA repair protein (Agrobacterium fabrum C58)
MAKAKTQFVCQNCGTVHNRWAGKCEGCGEWNTIVEEDPMGGIGSGPGKVPKKGRPVTLTS
LSGEIEEAPRIPTGISELDRATGGGFVRGSAVLIGGDPGIGKSTLLMQAAAALSRRGHRV
IYVSGEEAVAQVRLRAQRLGSADTDVLLAAETNVEDILATVSEGKRPDLIIIDSIQTLWS
DTADSAPGTVTQVRTGVQAMIRFAKQTGATMVLVGHVTKEGQIAGPRVVEHMVDAVLYFE
GDRGHHYRILRTVKNRFGPTDEIGVFEMSDGGLREVSNPSELFLGERNEKSPGAAVFAGI
EGTRPVLVEVQALVAATSLGTPRRAVVGWDSSRLAMILAVLEAHCGVKLGQHDVYLNVAG
GYRISEPAADMAIASALVSSLAGLALPADCVYFGEISLSGAVRPVAHTVQRLKEAEKLGF
SAALLPSGSAELPKAGKGRWTEIESLPDLVAHIAGSGNRFKQVEDDEY