Protein Info for Atu1048 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 transmembrane" amino acids 26 to 46 (21 residues), see Phobius details amino acids 78 to 101 (24 residues), see Phobius details amino acids 110 to 134 (25 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 232 to 257 (26 residues), see Phobius details PF00528: BPD_transp_1" amino acids 92 to 262 (171 residues), 93.8 bits, see alignment E=5.8e-31

Best Hits

KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 100% identity to atu:Atu1048)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, transmembrane component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJJ7 at UniProt or InterPro

Protein Sequence (272 amino acids)

>Atu1048 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MSAIMESSVAAEPRKPLIERVNWVKAAPWLYTLALFALWELLVYALKMPPTILPSPIRVG
QVIVQYWSPIWKNSLQTLYTTTLGFAIAVAAGLAIGLFIGWSKTIYAGLYPLMIGFNAIP
KVALVPILVIWFGIGTVPAVLTAFLISFFPIVVNVATGLATIEPETEDVLRALGAKKMDI
MLKVGIPRSMPYFFGSLKIAITLAFVGSVVSETVASNYGLGNMMSSAQSQFNVPLVFAGL
LMLAVEGIAMYAVMAWLEKRMTGWAHRSTMGQ