Protein Info for Atu0988 in Agrobacterium fabrum C58

Annotation: molecular chaperone, Hsp70 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF00012: HSP70" amino acids 109 to 239 (131 residues), 29.6 bits, see alignment E=2.3e-11 amino acids 311 to 407 (97 residues), 34.9 bits, see alignment E=5.6e-13

Best Hits

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 100% identity to atu:Atu0988)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D073 at UniProt or InterPro

Protein Sequence (432 amino acids)

>Atu0988 molecular chaperone, Hsp70 family (Agrobacterium fabrum C58)
MTQKRALGLDFGTTNTVMALSDTGSASHSMRFTSSAGTDDSMRTALSFMKDAGLGAAALH
VEAGQAAIRQFIDNAGDCRFLQSIKTFAASPLFQGTLIFAKRQSFEDLMEVFLRKLKTYA
GSEWPGDVSTVIAGRPVRFAGSNPDETLALARYNEALTRAGFPEIHYVYEPVAAAYYFAQ
SLKKDANVLVADFGGGTTDYSLIRFETHAGKLSATPIGHSGVGVAGDHFDFRMIDNLVSP
EIGKGSKFKSFDKVLDVPSGYYVNFGRWNQLSIFKTSKEFTDLKSLVRSALEPDKLELFI
DLVEHDEGYPLYQAISATKMALSSAQEAEFNFSPLGKAGRKMVKRSDFNNWIADDLAKIE
GALDEVLEKTKVAPEAIDKVFLTGGTSFVPAVRELFTRRFDADRIESGGELLSIAHGLAM
IGESGDIQRWTA