Protein Info for Atu0978 in Agrobacterium fabrum C58

Annotation: two component response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF00072: Response_reg" amino acids 30 to 140 (111 residues), 82.7 bits, see alignment E=2.2e-27 PF00486: Trans_reg_C" amino acids 173 to 248 (76 residues), 99.6 bits, see alignment E=8.2e-33

Best Hits

Swiss-Prot: 46% identical to COPR_PSEUB: Transcriptional activator protein CopR (copR) from Pseudomonas syringae pv. tomato

KEGG orthology group: K02483, two-component system, OmpR family, response regulator (inferred from 100% identity to atu:Atu0978)

Predicted SEED Role

"response regulator in two-component regulatory system with PhoQ" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJM7 at UniProt or InterPro

Protein Sequence (252 amino acids)

>Atu0978 two component response regulator (Agrobacterium fabrum C58)
MENKVQEMSVTSLSGCAEKGDGAIVPHMKILVIEDDLEAAAYMTKAFREAGIVADHASDG
ESGLFMGCENAYDVLVIDRMLPRRDGLSVISELRRRGIETPVLILSALGQVDDRVTGLRA
GGDDYLPKPYAFSELLARIEVLGRRKGKPEQDMIYRVGDLELDRLSHDVRRGGKEILLQP
REFRLLEYLMKNAGQVVTRTMLLENVWDYHFDPQTNVIDVHVSRLRSKIEKDFEKPLLKT
IRGAGYMMKDEG