Protein Info for Atu0938 in Agrobacterium fabrum C58

Annotation: transcriptional regulator, MerR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 125 PF00376: MerR" amino acids 1 to 24 (24 residues), 35.2 bits, see alignment 1.3e-12 TIGR02044: Cu(I)-responsive transcriptional regulator" amino acids 1 to 111 (111 residues), 153.7 bits, see alignment E=1.3e-49 PF13411: MerR_1" amino acids 2 to 53 (52 residues), 47.4 bits, see alignment E=2.5e-16 PF09278: MerR-DNA-bind" amino acids 29 to 93 (65 residues), 71.2 bits, see alignment E=1.3e-23

Best Hits

Swiss-Prot: 61% identical to HMRR_SINMW: HTH-type transcriptional regulator HmrR (hmrR) from Sinorhizobium medicae (strain WSM419)

KEGG orthology group: None (inferred from 100% identity to atu:Atu0938)

Predicted SEED Role

"Cu(I)-responsive transcriptional regulator" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJP6 at UniProt or InterPro

Protein Sequence (125 amino acids)

>Atu0938 transcriptional regulator, MerR family (Agrobacterium fabrum C58)
MIRYYEQIGLITPAARTGNNYRVYGEQDVHNLRFIKRARTLGFSLEETETLLKLWQDKSR
ESSAVKEIALVHIADLEQKIAEMKSMVKTLSHLAHCCGGDHRPDCPILDDLAGADKTDGK
PARTH