Protein Info for Atu0931 in Agrobacterium fabrum C58

Annotation: penicillin binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 757 transmembrane" amino acids 47 to 58 (12 residues), see Phobius details amino acids 83 to 110 (28 residues), see Phobius details amino acids 244 to 260 (17 residues), see Phobius details PF00912: Transgly" amino acids 142 to 306 (165 residues), 204.7 bits, see alignment E=7.8e-65 TIGR02074: penicillin-binding protein, 1A family" amino acids 145 to 668 (524 residues), 574.3 bits, see alignment E=1.4e-176 PF00905: Transpeptidase" amino acids 396 to 637 (242 residues), 83.9 bits, see alignment E=1.2e-27

Best Hits

KEGG orthology group: K05366, penicillin-binding protein 1A [EC: 2.4.1.- 3.4.-.-] (inferred from 100% identity to atu:Atu0931)

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-, 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.- or 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJP9 at UniProt or InterPro

Protein Sequence (757 amino acids)

>Atu0931 penicillin binding protein (Agrobacterium fabrum C58)
MVLRREWVETQKYRRAALPRTGKHRQVQEEKDDNKGRRKRHILLRIDSFIDSGLWTAAAR
LVDFWEDVTIASRKLHVRGWKKLVVNLTCDALTFGTAGSIVLLALAMPAFEETKKDWRYR
GDFAVTFLDRYGNTIGHRGIIHEDSVPIDQMPDHFIKAVLATEDRRFFDHFGIDFIGLAR
AMSENARAGGVVQGGSTLTQQLAKNLFLTNERSLERKIKEAFLALWLESNMSKKEILSLY
LDRAYMGGGTFGAAAAAQFYFGKNLTDVTLSESAILAGLFKAPAKYAPHVNLPAARARAN
TVLSNLVQSGLMTEGQVIGARRNPATVIDRADVKAPDYFLDWAFDEVQRLAAEGKFKDHT
VVVRTTIDTGLQQAAEQAMEMELREYGEGYRVKQGAMVMIENGGGVRAMVGGRDYGESQF
NRATAALRQPGSSFKVYTYSAAMEKGMKPDTLISDAPVTWRGWSPQNYGRSYAGKVTLQV
ALAKSYNTVPVRLAKDVLGTQVIVDTAKAMGVATPLRSDKTIPLGTSEVTVLDQATAYAV
FPADGMQSRRHGIEQVMDYEGNVLYDFSHDEPPAKRVLSEEANSKMNQMLVTIPVMGTAR
RGALDNGIVSGGKTGTSQAYRDAWYVGFTGNYTTAVWFGNDEFTPMNNMTGGALPAMTYK
RLMDYAHQGMELRPIPGIQNLLPTGARPQPSAQVAAASATTAPAMPALTRPRSLSAEATR
VIRSIAKTMKEAPPLAVTTQKVAEATIRDGRDEAGRR