Protein Info for Atu0822 in Agrobacterium fabrum C58

Annotation: ABC transporter, membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 71 to 96 (26 residues), see Phobius details amino acids 106 to 131 (26 residues), see Phobius details amino acids 144 to 167 (24 residues), see Phobius details amino acids 208 to 233 (26 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 24 to 280 (257 residues), 408.8 bits, see alignment E=9.8e-127 TIGR00969: sulfate ABC transporter, permease protein" amino acids 27 to 280 (254 residues), 321.3 bits, see alignment E=5.2e-100 PF00528: BPD_transp_1" amino acids 86 to 280 (195 residues), 36.8 bits, see alignment E=1.8e-13

Best Hits

Swiss-Prot: 54% identical to CYSW_SYNY3: Sulfate transport system permease protein CysW (cysW) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 100% identity to atu:Atu0822)

MetaCyc: 52% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CJU8 at UniProt or InterPro

Protein Sequence (290 amino acids)

>Atu0822 ABC transporter, membrane spanning protein (Agrobacterium fabrum C58)
MSETASRTSPRPFRDPASESLPARLALIAVAFLFLAAFLVLPLVSVFFEAFRKGADSFWD
AIVEPDALSAIRLTLLVAAISVPLNVVFGVAAAWAIAKFEFKGKAFLITLIDLPFSISPV
ISGLVYVILFSAHSVLGPWLKSYGIEILFAVPGIVLATIFVTFPFVARELIPLMQDQGNG
DEEAAISLGASGWQTFWYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGETNTM
PLHVEILYNEYNIGASFAVATLLAGLALVTLVLKTILEIRFGAGNAAGKH