Protein Info for Atu0817 in Agrobacterium fabrum C58

Annotation: sulfate adenylate transferase, subunit 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 TIGR02039: sulfate adenylyltransferase, small subunit" amino acids 24 to 317 (294 residues), 519.8 bits, see alignment E=1.2e-160 PF01507: PAPS_reduct" amino acids 44 to 271 (228 residues), 190.3 bits, see alignment E=1.5e-60

Best Hits

Swiss-Prot: 100% identical to CYSD_AGRFC: Sulfate adenylyltransferase subunit 2 (cysD) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K00957, sulfate adenylyltransferase subunit 2 [EC: 2.7.7.4] (inferred from 100% identity to atu:Atu0817)

MetaCyc: 84% identical to sulfate adenylyltransferase beta subunit (Sinorhizobium meliloti)
Sulfate adenylyltransferase. [EC: 2.7.7.4]

Predicted SEED Role

"Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)" in subsystem Cysteine Biosynthesis (EC 2.7.7.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.4

Use Curated BLAST to search for 2.7.7.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D0L8 at UniProt or InterPro

Protein Sequence (317 amino acids)

>Atu0817 sulfate adenylate transferase, subunit 2 (Agrobacterium fabrum C58)
MSNAVHETDSKNTVASKPPLDPHLKALENEAIHIFREVAAEFDNPVMLYSIGKDSSVLLH
LARKAFFPGRIPFPLLHVNTGWKFKEMIEFRDNIVKEYDLDLISYTNPRGALENVTPFSH
GSALYTDIMKTEALRQALDAGQFDAAFGGARRDEEASRAKERIYSFRTPDHKWDPRNQRP
ELWNIYNGMVRKGESVRAFPLSNWTEVDIWRYIEAENIPLVPLYYAAERPYIERDGMMIL
AEDERLELLPGEEIKHGSIRFRTLGCFPLTGAIRSEAATLQDVIAELEIATVSERQGRAI
DRDQSGSMEKKKREGYF