Protein Info for Atu0786 in Agrobacterium fabrum C58

Annotation: peptidase, family M16

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF00675: Peptidase_M16" amino acids 14 to 160 (147 residues), 159.1 bits, see alignment E=8e-51 PF05193: Peptidase_M16_C" amino acids 166 to 339 (174 residues), 123.8 bits, see alignment E=7.7e-40

Best Hits

KEGG orthology group: K01422, [EC: 3.4.99.-] (inferred from 100% identity to atu:Atu0786)

Predicted SEED Role

"Mitochondrial processing peptidase-like protein (EC 3.4.24.64)" in subsystem ZZ gjo need homes (EC 3.4.24.64)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.64 or 3.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D0P0 at UniProt or InterPro

Protein Sequence (432 amino acids)

>Atu0786 peptidase, family M16 (Agrobacterium fabrum C58)
MRVNVTRLSSGLTVVTERMPHLESVALGVWIKSGSRNETTAEHGIAHLLEHMAFKGTARR
TARQIAEEIENVGGEVNAATSTETTSYYARVLKDHVPLAVDILADILTESLFDEDELERE
KNVILQEIGAATDTPDDVIFDNFSGVAYRDQTIGRPILGTPDTVQSFTSGEIRHYLARNY
TTDRIFVVAAGAVDHESFVKQVEERFASLPLVPAAPPVMEKAIYTGGEIRETRDLMDAQV
LLGFEGKAYHARDFYCSQILANILGGGMSSRLFQEVREARGLCYSVYAFHWGFSDTGIFG
VHAATGGNDLPELIPVIVDELRKSSETIHQDEINRARAQIRAQLLMGQESPAARAGQIAR
QMMLYGRPIPNEEMMTRLEDITRERLTDLAGRLFFDTVPTLSAIGPLEQLPPLSDITAAL
SAQQPARIKANG