Protein Info for Atu0704 in Agrobacterium fabrum C58

Annotation: 2-dehydro-3-deoxygalactonate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF05035: DGOK" amino acids 10 to 297 (288 residues), 333.6 bits, see alignment E=3.9e-104

Best Hits

KEGG orthology group: K00883, 2-dehydro-3-deoxygalactonokinase [EC: 2.7.1.58] (inferred from 100% identity to atu:Atu0704)

Predicted SEED Role

"2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58)" in subsystem D-galactonate catabolism (EC 2.7.1.58)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.58

Use Curated BLAST to search for 2.7.1.58

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D0W1 at UniProt or InterPro

Protein Sequence (304 amino acids)

>Atu0704 2-dehydro-3-deoxygalactonate kinase (Agrobacterium fabrum C58)
MSEPAFIAVDWGTTSFRLWLLSRSGAVLAERRSAEGMTTAMRTGFADVLQAHLDAIGAPA
DLPVLVCGMAGARQGWVEAGYIDVPASLSAVLEGAVRVPGQTRDVRILPGLAQRDKGAPD
VMRGEETQLLGALSSGDSGEKLVCMPGTHSKWVTVKDGGVTRFATFMTGELFEAISKQTI
LSHAVAEAEAFTGEHEAFTAAVRDIYAHPELATNRLFTLRSGQLLHGLAATDAKARLSGI
MIGLEIAGAHSQAKRETPVVLIGSGALGALYEGAFTALDIHYTVIDADDAVRRGLLAAAN
AIWP