Protein Info for Atu0692 in Agrobacterium fabrum C58

Annotation: glutathione-regulated potassium-efflux system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 50 (19 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 216 to 234 (19 residues), see Phobius details amino acids 240 to 258 (19 residues), see Phobius details amino acids 270 to 289 (20 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 329 to 352 (24 residues), see Phobius details amino acids 358 to 378 (21 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 13 to 375 (363 residues), 208.4 bits, see alignment E=1.6e-65 TIGR00932: transporter, monovalent cation:proton antiporter-2 (CPA2) family" amino acids 16 to 285 (270 residues), 253.8 bits, see alignment E=1.1e-79 PF02254: TrkA_N" amino acids 404 to 514 (111 residues), 74.2 bits, see alignment E=1.1e-24

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 100% identity to atu:Atu0692)

Predicted SEED Role

"putative Glutathione-regulated potassium-efflux system protein KefB" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CK13 at UniProt or InterPro

Protein Sequence (610 amino acids)

>Atu0692 glutathione-regulated potassium-efflux system protein (Agrobacterium fabrum C58)
MTEHDALFSEPLLLLAGAVIAASVFRKLGLGTVLGYLVAGIIIGPFLHLVTDAKDIFNVS
ELGVVFLLFIIGLELKPSRIWQMRRDILGLGLAQVLVTGSALAAIAWWAGLIDARGSVVA
GFGLALSSTAFALQILEDDGDMNTRHGNRSFSILLFQDLAIVPLLALVTILSNRPDVPTD
SMAYDLVASVVAVAGMVLAGRFLLTPMFQIIARTGAREVMIAAALFVVIGAAAIMEMVGL
SMGMGALLAGLMLSESSYRHELEADIEPFRGLFLALFFMAVGMSLHINIVYEHIVLILIA
VPVMMAVKAALIYGLCRIAGSSRYASSRIALLLAQGGEFGFVLFTTAAASGLFPQATASI
LVAVVTLSMALTPVLAVISRRLTAEDAEEDKLEEDFDGAGADVLMIGFSRFGQIASQILL
AGGRDVTVIDSSADRVRQAARFGFRIFFGDGTRKDVLIAAGIERADLVAVCTHKKEVTDR
IIDMIQSEFPSVRIYARSYDRIHSLDLRKKGVEYEIRETLESGLLFGRRILEGLDMDAER
ALAISDDIRERDEQRLELQAVEGLAAGRQMLHNKPVREVKPEPLMKPKNKAEKREEEEED
MEESETEVLL