Protein Info for Atu0614 in Agrobacterium fabrum C58

Annotation: two component sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1275 PF13188: PAS_8" amino acids 783 to 820 (38 residues), 19.4 bits, see alignment (E = 2.3e-07) amino acids 909 to 959 (51 residues), 21.2 bits, see alignment (E = 6.5e-08) TIGR00229: PAS domain S-box protein" amino acids 907 to 1029 (123 residues), 44.5 bits, see alignment E=8e-16 PF00989: PAS" amino acids 908 to 971 (64 residues), 31 bits, see alignment 6.5e-11 PF13426: PAS_9" amino acids 919 to 1021 (103 residues), 22.7 bits, see alignment E=3e-08 PF00512: HisKA" amino acids 1043 to 1111 (69 residues), 61.4 bits, see alignment 2.1e-20 PF02518: HATPase_c" amino acids 1158 to 1270 (113 residues), 76.2 bits, see alignment E=8.2e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu0614)

Predicted SEED Role

"Sensory histidine kinase AtoS" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D135 at UniProt or InterPro

Protein Sequence (1275 amino acids)

>Atu0614 two component sensor kinase (Agrobacterium fabrum C58)
MPAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQG
PKRQDVTFRQLAATAARLSKAGDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSA
LTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAASSGFSSLGITPHTARTLIKMA
AGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSED
RDVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELP
SDFEEDVAAEQDEDGLLSMPDDKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVA
PSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAADDELTTETETANIGTGEEARP
FVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKI
RELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDP
HATGLTFLNSEETEPAEVLPQQAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIA
GDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVHLEDRRSRSREGLTAGEQAAF
REIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPV
EEDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTA
ETLDQMPVALLVHAGDRLIHANPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEG
GMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKPAAVMAANENTAENAEAGSNL
SLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHE
SQRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDIT
QWKRTEEELRNAKRAAETANAHKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPR
YVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAVPLNETVAEAVSLVQPQANNQ
RVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIR
DTGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEG
TLVEITFPSQRVLAN