Protein Info for Atu0510 in Agrobacterium fabrum C58

Annotation: pH adaption potassium efflux system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 31 to 52 (22 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 90 to 111 (22 residues), see Phobius details amino acids 120 to 159 (40 residues), see Phobius details amino acids 171 to 195 (25 residues), see Phobius details amino acids 216 to 241 (26 residues), see Phobius details amino acids 249 to 276 (28 residues), see Phobius details amino acids 289 to 308 (20 residues), see Phobius details amino acids 315 to 333 (19 residues), see Phobius details amino acids 340 to 361 (22 residues), see Phobius details amino acids 399 to 428 (30 residues), see Phobius details amino acids 449 to 467 (19 residues), see Phobius details amino acids 487 to 508 (22 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 138 to 436 (299 residues), 120.6 bits, see alignment E=4e-39

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 100% identity to atu:Atu0510)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D1B3 at UniProt or InterPro

Protein Sequence (547 amino acids)

>Atu0510 pH adaption potassium efflux system protein (Agrobacterium fabrum C58)
MSFPFHIVVAPILLPLITAALLLFFDERQRVAKAAISFTSTVLLLIVAILLFREVNSTVN
TEIAAVVSSGVYLLGNWPAPFGIVLVADRLSGLMVLLTALLAIPSLIYSMAKWHKSGAHF
HSLFQMMLMGVNGAFLTGDLFNLFVFFEVMLAASYGLLLHGSGQQRVKAGLHYIAINLVA
ALFFLIGVSLIYGVTGTLNMGDLAHRIEGLNPDQRMLLETGAAILGIAFLVKAGMWPLNF
WLPSAYGAASAPVGGLFAIMSKVGIYVIARLSFLLFGQTAGESAGFGHDALLVGGIATII
FGAIGVLASQALGRLAGFSVLVSSGTLLAAMGTGNPTVAAGALYYMVSSTLTISAFFMLI
ELVERGQDAGANVLAVTMEAYGEGEEEDEEEEVGVTMPATIAVLGACFAACGILLAGLPP
LSGFIAKFSMLTAILNPSGLGANDSVSTLSWWLVFLIVFAGFASLVSMTRAGIRTFWASI
EGTVPRVLVIEIAPIMLLLGLTLAMTIQAGPVMRYMQETARILDLPASYIQGVISAPRAG
SNPEAEP