Protein Info for Atu0434 in Agrobacterium fabrum C58

Annotation: 2'-deoxycytidine 5'-triphosphate deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF06559: DCD
  • amino acids 10 to 368 (359 residues), 584.1 bits, E=4.6e-180

Best Hits

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 100% identity to atu:Atu0434)

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Sequence Analysis Tools

See A9CKA1 at UniProt or InterPro

Protein Sequence (370 amino acids)

>Atu0434 2'-deoxycytidine 5'-triphosphate deaminase (Agrobacterium fabrum C58)
MTRTTGTRTTGILADGAIRALFAGDKLKSEADLDVDQVQPASLDLRLGSKAYRVRASFMP
GPGTRVIDKLNRFSLHEVDLSQGAVLETGCVYIVPLMESLALPADMSASANPKSSTGRLD
IFTRVMTDNAQEFDKIPAGYTGPLYLEISPRTFPIVVRRGSRLSQIRFRIGHALLNESEV
LKLHETETLVASENPNVTGGGIALSIDLKGFGENGLIGYRGKHHTAVVDVDKKAQHDVLD
FWEPLFARGRAELILDPDEFYILVSREAVHVPPLYAAEMTPFDPLVGEFRVHYAGFFDPG
FGHAQAGGTGSRAVLEVRSHEVPFILEHGQIVGRLVYEHMLEKPEGLYGTGLGSNYQAQG
LKLSKHFRAE