Protein Info for Atu0346 in Agrobacterium fabrum C58

Annotation: uridylyltransferase/uridylyl-removing enzyme UTase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 942 TIGR01693: protein-P-II uridylyltransferase" amino acids 51 to 909 (859 residues), 1060.4 bits, see alignment E=0 PF01909: NTP_transf_2" amino acids 97 to 155 (59 residues), 27 bits, see alignment 1.2e-09 PF08335: GlnD_UR_UTase" amino acids 205 to 343 (139 residues), 152.1 bits, see alignment E=2.5e-48 PF01966: HD" amino acids 515 to 606 (92 residues), 47.7 bits, see alignment E=4.6e-16 PF01842: ACT" amino acids 730 to 781 (52 residues), 27.3 bits, see alignment 6.1e-10 amino acids 840 to 887 (48 residues), 35 bits, see alignment 2.4e-12

Best Hits

Swiss-Prot: 100% identical to GLND_AGRFC: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 100% identity to atu:Atu0346)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UIF1 at UniProt or InterPro

Protein Sequence (942 amino acids)

>Atu0346 uridylyltransferase/uridylyl-removing enzyme UTase (Agrobacterium fabrum C58)
MAIKDLDFSDILDVSALKRDCDVIFKEDSKRIADIKSDLLPIFRRASTEGREKARELLKA
DGSGIDCARRISWLQDRLIETLYDLACQHVYPKDAPQIAVAAVGGYGRGTLAPGSDIDLL
FLLPAKNTPDMHKAVEFVLYLLWDLGFKVGHATRTVDECIRLSKSDMTIRTAILEVRAIC
GRKSLTDDLEKRFESEVVTGTGPEFIAAKLAERDQRHRKAGDTRYLVEPNVKEGKGGLRD
LHTLFWIAKYYYHVRDTADLVKLGVLSRSELKLFEKADDFLWAVRCQMHFITGKAEERLS
FDIQREIADALNYQPRPGLSAVERFMKHYFLVAKDVGDLTRIVCAALEDRQAKDVPGLSG
VLSRFAHRVRKIPGSVEFVEDRGRIALARPDVFKNDPVNLIRLFHIADINNLELHPDALR
VVTRSLSLINDELRENEEANRLFLSILTSRRDPALTLRRMNEAGVLGKFIPEFGKIVAMM
QFNMYHHYTVDEHLIRSVGVLSEVDKGTAVDAHPLANQLMPGVEEREALYVAVLLHDVAK
GRQEDHSIAGARVARKLCQRFRLTGKQTETVVWLIEQHLLMSMVAQTRDLHDRKTITDFA
DKVQSMERLKMLLILTVCDIRAVGPGVWNGWKGQLLRSLYYETELLLSGGFSEVSRKERA
QIARQALYDALEDWGQKARRKYTKLHYEPYLLTVALEDQVRHTRFMREADKQEKALSTMV
RTHSFHAITEITVLAPDHPRLLSIITGACAAAGANIADAQIFTTSDGRALDTILINREFP
IDEDETRRGANVGKLIEEVLSGKQRLPEMIATRTKSRRKKSAFTIPPSVTISNGLSNKFT
VIEVECLDRPGLLADMTAVIADLSLDIHSARITTFGEKVIDTFYVTDLFGQKVTNDNRQA
SIAQRLKAVMSEQEDELRDRMPNGIIAHPDVAALPAARTAKA