Protein Info for Atu0260 in Agrobacterium fabrum C58

Annotation: aldo-keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00248: Aldo_ket_red" amino acids 15 to 311 (297 residues), 265.2 bits, see alignment E=3.1e-83

Best Hits

Swiss-Prot: 51% identical to ALKR1_ARATH: Probable aldo-keto reductase 1 (At1g10810) from Arabidopsis thaliana

KEGG orthology group: None (inferred from 100% identity to atu:Atu0260)

Predicted SEED Role

"Aldo-keto reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U5N2 at UniProt or InterPro

Protein Sequence (333 amino acids)

>Atu0260 aldo-keto reductase (Agrobacterium fabrum C58)
MKKRTLGNNLSVSALGLGCMGMTHAYSPTGDENSAIATLHRAVELGVTFFDTAEVYGPYN
NEILVGKGLKPYRDKVVIATKFGFRIDPSKPAGQMMVGTDSRPENVRAVAEASLKRLGVD
VIDLFYQHRVDPNVPIEDTLGAMAELVQQGKVKYLGLSEASAETLRKAHAVHPIAAIQSE
YSLWTRDVEENGVLETCRELGIGFVPFSPLGRGALTGALKSLDGLAADDFRRGLPRFQSE
NFDANLALIKLLEDMAAEKGVTAGQLALAWVLAQGDFIVPIPGTTKIANLEKNVAATDVS
LTADEVASLGALLSPAKVAGERYPERMSQMANR