Protein Info for Atu0216 in Agrobacterium fabrum C58

Annotation: components of type IV pilus

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 transmembrane" amino acids 15 to 36 (22 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details amino acids 300 to 322 (23 residues), see Phobius details PF00482: T2SSF" amino acids 189 to 317 (129 residues), 79.4 bits, see alignment E=1.2e-26

Best Hits

KEGG orthology group: K12511, tight adherence protein C (inferred from 100% identity to atu:Atu0216)

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CKJ8 at UniProt or InterPro

Protein Sequence (328 amino acids)

>Atu0216 components of type IV pilus (Agrobacterium fabrum C58)
MTGDLFSRLTDPQTIIAILVTLAVFATLYTLIMPFLERKDLAKRMKAVSSERELIRSRER
ERLATVTRDGRTSLRGNNNKSARRIVEKFNLREALADQNTMNKLRAAGFRSQNALNTFLA
ARFVLPFIFLAVAFTWVFVLGNLADKAFVVRLMAVLVFGYIGFYAPNIYVSNRMTKRQAS
IKRAWPDALDLMLICIESGVSMESAMRRVAEEMGEQSPELAEEMILTTAELSFLQDRRTA
LENFGMRTQLDGVKSVVQALIQAERYGTPLAQALRVLAQEGRDERMNEAEKKAAALPPKL
TVPMIIFFLPVLIAVILGPAGIRVADTF