Protein Info for Atu0138 in Agrobacterium fabrum C58

Annotation: surfeit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 37 to 58 (22 residues), see Phobius details amino acids 242 to 263 (22 residues), see Phobius details PF02104: SURF1" amino acids 49 to 253 (205 residues), 186.8 bits, see alignment E=3.3e-59

Best Hits

KEGG orthology group: K14998, surfeit locus 1 family protein (inferred from 100% identity to atu:Atu0138)

Predicted SEED Role

"Cytochrome oxidase biogenesis protein Surf1, facilitates heme A insertion" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D246 at UniProt or InterPro

Protein Sequence (276 amino acids)

>Atu0138 surfeit 1 (Agrobacterium fabrum C58)
MRAERGPPKQTISLPVALRKDRDMSEIAPQNRRIRPAAIVVLFLTIALTGCLLALGTWQV
QRLFWKLDLIERVDVRAHAEPVDAPAASDWPALGNPSDYEYRRVKLTGTLLNDREVQVYT
VTDLGPGYWVMTPLRRDDGSSIIVNRGFVPSDRRDPSSRTGGEPTGNVEIVGLMRAPETG
GLFLRTNDPANGRWYSRNIPQITQASGLSDVAPFYVDADATPNPGGLPVGGKTMLTFPNN
HLSYAVTWYILAAMVVAAGWYVLRNLNAPKSKRDAD