Protein Info for Atu0052 in Agrobacterium fabrum C58

Annotation: helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 828 TIGR01970: ATP-dependent helicase HrpB" amino acids 15 to 827 (813 residues), 1008.5 bits, see alignment E=1.4e-307 PF00270: DEAD" amino acids 27 to 172 (146 residues), 44.7 bits, see alignment E=1.9e-15 PF00271: Helicase_C" amino acids 215 to 339 (125 residues), 51.8 bits, see alignment E=1.3e-17 PF08482: HrpB_C" amino acids 683 to 814 (132 residues), 158.6 bits, see alignment E=1.7e-50

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to atu:Atu0052)

Predicted SEED Role

"macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif."

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D2A3 at UniProt or InterPro

Protein Sequence (828 amino acids)

>Atu0052 helicase (Agrobacterium fabrum C58)
MTRTPVPIKTELPELPVSAVLGDIAQVLAAKKRAVLSAPPGAGKTTLVPLRLLHEDWRGD
GKIILLEPRRLAARAAAGRMAELLRENVGETVGYRMRLDNRVSSKTRIEVVTEGVFARMV
LDDPELSGVSTVIFDEFHERSLDGDFGLALALDVQAGLREDLRILVMSATLDVERIGALM
GDAPVIQSLGRTFPIDIRYEERWQGIHVDEKVAKAITEAHASETGSILAFLPGQAEITRT
ASRLEGRFPDDTDIIPLYGNLSQKEQDAAIKPAPGGRRKIVLATSIAETSITIDGVRVVI
DSGLQRLPVFEPATGITRLETVRVSRASADQRAGRAGRTEPGIAIRLWHQGQTAALNAFT
PPQILASDLSGLALDLAHWGVHDPSALAFLDAPPEAALKESVALLKNLGALDNSGGLTRQ
GHLMRGLSLPPRLAAMVIASAEEGAGKKAAMLAVMLTEQGLGGNDIDLDERLRRFFSERS
ERAQAARKLASRLLDAIGDKTAKAETPSEVGALLLHAYPDRIALQRGARGRYVMANGRGA
ELAETERLAASKMLVVADITGRAAQPRVLAAAAIERADIEERMPHLIVQQEQLLFDKASG
QARARKVTRLGAIILDETPLPRPDGEQAARALANGVREFGLDILPFSKETLQLRDRIGFL
NASIGDPWPDVSDAALLARLEEWFVPFQNGARSLQDIRPGSLSEGILSLVPHEVARDLGR
LAPTHFEAPTGQRHPIRYDASEPTLSIRVQELFGLKAHPAIAQGRLPLLLELTSPAHRPI
QTTRDLPGFWTGSWKDVRADMRGRYPRHPWPEDPASALPTSRAKPRGT