Protein Info for Atu0023 in Agrobacterium fabrum C58

Annotation: ATP-dependant DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1185 TIGR02784: double-strand break repair helicase AddA" amino acids 24 to 1169 (1146 residues), 1632.3 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 26 to 481 (456 residues), 164.3 bits, see alignment E=1.2e-51 PF13245: AAA_19" amino acids 34 to 467 (434 residues), 40.4 bits, see alignment E=8.5e-14 PF13361: UvrD_C" amino acids 588 to 894 (307 residues), 62.5 bits, see alignment E=1.2e-20 PF12705: PDDEXK_1" amino acids 1009 to 1154 (146 residues), 52.4 bits, see alignment E=1.8e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu0023)

Predicted SEED Role

"FIG061771: ATP-dependent nuclease subunit A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D2B8 at UniProt or InterPro

Protein Sequence (1185 amino acids)

>Atu0023 ATP-dependant DNA helicase (Agrobacterium fabrum C58)
MTIDPFDAGPAADTPESWIDWTSARQRLASDPASSAWVSANAGSGKTHVLTQRVIRLLLA
GCRPSAILCLTYTKAAASEMSSRVFDRLAEWATLPDSDLKDRITTIEGKVPDRIKLAEAR
RLFAKALETPGGLKIQTIHAFCEALLHQFPLEANVAGHFSVLDDRAATTLLAEARRSLLT
AVSTEDDAELVQALAYVLDLADESGLEALLSAIIANRSALRSFLHEAKQSGGLDVRLRQE
MQIAAGETEETAAEAFWPLPGLSGLVLDTYLTLADEVGGSRVIEVAYALREAKRQPDPVR
RMELIEAALLTAKGEKKSDAYVINKGMQKSAPDLVDALTLARDHVVACRNRYRLVRMLVA
TKSALVLAERLIGDFEDLKKQRSQLDFEDLIERAANLLNRDTAGAWVHYKLDQGIDHILV
DEAQDTSPVQWSIIQSLAADFFNGESARMGRRTLFAVGDEKQSIYSFQGARPERFSQERD
ETKRRVDQVEQAFHRIRLPLSFRSTEDVLAAVDQVFSDPKNASGLSADNEPVEHRSNRAG
HPGTVEVWDMVAPETTEDEEDWTAPFDALRESAPATIVARRIAARIADMIGNQTIIEKGV
ERAVEPGDILVLVRKRAAFVNALTRELKRRKNIPVAGADRLRLTDHIAVQDLLALGRFVV
LPEDDLSLAALLKSPLFNLTEDDVFEIAATRSEAESVWQRLQVLSGEETSRLSIVTDKLR
HFISLSKTATVHDFFAAVLTLHDGRKKFLGRLGNEASDVLDEFLSFALDHERTGLPGLQA
FLSVLETDSPEVKREQDKDRGEVRIMTVHASKGLEAPVVFVVDGGSKAFNHSHVPKLRFV
EGDGDAFPVWLPGSGFSNHLIRSDEERLKTAAEDEYRRLLYVAMTRAADHLVVCGYRGQK
ENPECWHAIVKAALAENQDHCQPQAFSADGEEWQGLVWRKSEARPALAPHKPAEPQQEED
HTLPPGLLAPLPALPSLPRPLSPSGAGTIIDDGADDLAVRSPLFGEKTEASSLALQRGKL
VHRMLQALPDFAESEREEAARRYAERAARFWPATDRERLIQAVLRVLSEPAVQPAFSANS
RAEVSIMGTMTLGRQHYAVSGRIDRLAVERDRVILVDYKTNRVPPREARELPFSHVAQLA
IYREILAPLYPGKEFVCALIYTESAAFVRVDDDAMAEALAAIKTK