Protein Info for AMB_RS23225 in Magnetospirillum magneticum AMB-1

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 transmembrane" amino acids 17 to 36 (20 residues), see Phobius details amino acids 154 to 178 (25 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 233 to 394 (162 residues), 151.8 bits, see alignment E=7.4e-49 PF00990: GGDEF" amino acids 235 to 391 (157 residues), 162.9 bits, see alignment E=5.7e-52 PF00563: EAL" amino acids 413 to 647 (235 residues), 251.3 bits, see alignment E=8.5e-79

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb1104)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W8B7 at UniProt or InterPro

Protein Sequence (684 amino acids)

>AMB_RS23225 GGDEF domain-containing protein (Magnetospirillum magneticum AMB-1)
MTMPLAHRTPKSIGRKLLLIVLPSLLFGTVVMFSAFEHYSVRDRLSALNSRLDSFAITQG
AALVKPLWEFDFAAVQRQFQSYPDVPELFEATVFGIGGEIVASAQGGDTDGRRDVFRKVV
PLIQQTPGGEYPVGRLEVAFHDGKVRSELVRQRAGAAIVLSGAFLLVTAVLLAAVRHLVT
GPLTRLRNSLHHNASVLMREPLVWSSRDELGEVVHAYNQLLTEIDQRTEDIHQLANRDLL
TGLPNRRLLEDRIGHAIALAGRQNRSIALLFADIDNFKVVNDTLGHKQGDALLRIIADRI
HDIMRGMDTVARWGGDEFVIVVESLNSAGEAASVAEKLIETIGVPVQLGSNLLRVGVSVG
ISMYPQDGADITTLIKNADMALFEAKGRGRNTFHFFDQAMNARALRRMDIEMALRQAIPQ
NQLELHYQPKIASASGALAGVEALVRWRRPGEGLVQPDEFIPLAEESDLIVAVGEWVLNE
ACRQIRDWEARGFGEVAVAVNLSPRHFLHEKDVDGIFRIVDQSGVRPDLIEVEVTESTFM
HEPEKVIGYLNRLRDRGFGIAIDDFGSGYSSLSYLRRLPITTLKIDRAFVMDIEHNADNA
EIIRAIIAMANAMGLGLIAEGVENRHQFEFLRHADCGVVQGYYFSRPLPPADLEAQLVRQ
GADSMAPLSLSASQTGLQPVFATS