Protein Info for AMB_RS23095 in Magnetospirillum magneticum AMB-1

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 transmembrane" amino acids 300 to 318 (19 residues), see Phobius details PF13649: Methyltransf_25" amino acids 148 to 233 (86 residues), 41.7 bits, see alignment E=2.4e-14 PF08242: Methyltransf_12" amino acids 148 to 235 (88 residues), 34.1 bits, see alignment E=5.7e-12 PF08241: Methyltransf_11" amino acids 148 to 237 (90 residues), 44.2 bits, see alignment E=3.7e-15

Best Hits

KEGG orthology group: K00563, 23S rRNA (guanine745-N1)-methyltransferase [EC: 2.1.1.187] (inferred from 100% identity to mag:amb0114)

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.187

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WB57 at UniProt or InterPro

Protein Sequence (332 amino acids)

>AMB_RS23095 class I SAM-dependent methyltransferase (Magnetospirillum magneticum AMB-1)
MSSCGRPGLSRGIFRNWAPAARPSHTARGAWAGLDCVGREGETVMIDIGHLFVCPLCREG
LTSSGDGYACTSCHRHFGKANGVWDFRVEPAAAEPPLYSDPFFRRHRECLAQLHAQHYGE
NSMSGQLEDRFKQVARKLMETEPDFVGDIGCGTGGAFSTFGPPSRMIGVDQDIKLLEVAA
RRYPEATLVCCDLLRSPLRQGAFPALICLCCLEHVYWLEDSLAVMHDLLAPGGRLYVMIP
TEGGLAWSTARNLFTLSVNAKISGMTNDQYRHVMRIEHCNNFEAVNSALFKFFEIERFNF
WPMGIGGHHLNLIGLYSLKRRTSQMMALASKS