Protein Info for AMB_RS22760 in Magnetospirillum magneticum AMB-1

Annotation: ribonuclease PH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 TIGR01966: ribonuclease PH" amino acids 2 to 236 (235 residues), 377.2 bits, see alignment E=1.2e-117 PF01138: RNase_PH" amino acids 10 to 140 (131 residues), 105.2 bits, see alignment E=3.5e-34 PF03725: RNase_PH_C" amino acids 159 to 223 (65 residues), 45.5 bits, see alignment E=6.1e-16

Best Hits

Swiss-Prot: 73% identical to RNPH_RHORT: Ribonuclease PH (rph) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K00989, ribonuclease PH [EC: 2.7.7.56] (inferred from 100% identity to mag:amb4498)

Predicted SEED Role

"Ribonuclease PH (EC 2.7.7.56)" in subsystem Heat shock dnaK gene cluster extended or tRNA processing (EC 2.7.7.56)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.56

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VYM3 at UniProt or InterPro

Protein Sequence (239 amino acids)

>AMB_RS22760 ribonuclease PH (Magnetospirillum magneticum AMB-1)
MRPSGRAPDQLRTVILETGVSRHAEGSCIAKFGDTHVLCTASVEEKVPPFLRNTGKGWVT
AEYGMLPRSTHTRTDREAAKGKQSGRTHEIQRLIGRSLRSVTDLAAMGERQIKIDCDVLQ
ADGGTRTASITGAFVALHLAFQRLVRLELLKAIPLTDHVAAISCGIYEGVAVLDLDYPED
SNAQADANFVMTGTGGIVEIQGTAEERPFSRTQFLELTDLAEAGIRQLVEAQKKALGLS