Protein Info for AMB_RS22650 in Magnetospirillum magneticum AMB-1

Annotation: [protein-PII] uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 929 TIGR01693: protein-P-II uridylyltransferase" amino acids 49 to 911 (863 residues), 946.9 bits, see alignment E=5.7e-289 PF01909: NTP_transf_2" amino acids 94 to 173 (80 residues), 25.4 bits, see alignment E=4.6e-09 PF08335: GlnD_UR_UTase" amino acids 207 to 345 (139 residues), 154.5 bits, see alignment E=5.6e-49 PF01966: HD" amino acids 488 to 615 (128 residues), 28.4 bits, see alignment E=5.1e-10

Best Hits

Swiss-Prot: 61% identical to GLND_AZOBR: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Azospirillum brasilense

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 100% identity to mag:amb4476)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VYP5 at UniProt or InterPro

Protein Sequence (929 amino acids)

>AMB_RS22650 [protein-PII] uridylyltransferase (Magnetospirillum magneticum AMB-1)
MSKIKGQRAIIHRKAIIARLDELSAEDLPKNKRRMKALEIFKQVLASGRAEVRARFDAHG
DGTATVRENCLLIDQLVRLVHDYACDREFPQGVRTAGETMSLVAVGGYGRGELSPHSDID
LLFLLPYKRMPYHEQVVEFILYMLWDMGLKVGHSTRSAEDCVRNAKADLTVRTALLEMRW
LWGDQALFEDLRTRYRAEIITGTAEAFVESKLAERDSRHSSMGDSRYVLEPNVKEGKGGL
RDLHTLYWIAKYVYRVENVAELAEKGIISRPAARRFAKAQAFLWAVRCHLHYLTDRPEDR
LTFDVQPEIAVRMHYADRACSRGVERFMKHYFLIAKDVGDLTRLFCAVTEETFKTKPRRL
QLGRLFSRRTIVGGFQLEGGRLDVCAQNQFETDPVGMIRLFHTALEHGVDIHPHALDLVH
RNLKRIDAGMRNDPAANRLFVEMLTSRKNPEVALRHMNEAGVLGRFIPDFGRVVAQMQYD
MYHVYTVDEHTVQALGILHAIERGDLKDEAPTSSEVIHQVVSRRALFVAVFCHDIAKGRG
GDHSTLGAEVVMKLGPRFGLTDEETESAAWLVREHLSMSRVAFKRDIDDSKTISDFVALV
QSPERLRLLLCLTVADIRAVGPTVWNAWKAGLLRELYSRALEVMTGGLSGTARAARIKAA
QDALRSELFKLSWPPEDIEAHIARGYSTYWTTFDTPIHLRHARLVREAEAVRAPLTVEPR
VDSHRAVTEIIVYTGDHPGLFSQIAGAMAVSGANIVDAKIITLANGMALDTFCIQDSDGG
AFDSPAKLAKLATCVEQVLSGRTRLDRELAARKGKLPSRAHVFKVPPRVLVDNMPSRSHT
VVEVNGRDRPGLLYDITNAMTNVGLQISSAHISTYGERVVDVFYVKDVFGHKIEHGRKLD
QIKAALLAALEDPAAKAAAKTGDGTKAAE