Protein Info for AMB_RS22605 in Magnetospirillum magneticum AMB-1

Annotation: apolipoprotein N-acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 22 to 49 (28 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 94 to 117 (24 residues), see Phobius details amino acids 126 to 145 (20 residues), see Phobius details amino acids 166 to 191 (26 residues), see Phobius details amino acids 200 to 220 (21 residues), see Phobius details PF20154: LNT_N" amino acids 26 to 185 (160 residues), 76.5 bits, see alignment E=2.8e-25 TIGR00546: apolipoprotein N-acyltransferase" amino acids 69 to 459 (391 residues), 290.5 bits, see alignment E=1.2e-90 PF00795: CN_hydrolase" amino acids 237 to 466 (230 residues), 70.3 bits, see alignment E=1.7e-23

Best Hits

KEGG orthology group: K03820, apolipoprotein N-acyltransferase [EC: 2.3.1.-] (inferred from 100% identity to mag:amb4467)

Predicted SEED Role

"Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE" in subsystem Phosphate metabolism or Copper homeostasis: copper tolerance (EC 2.3.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VYQ4 at UniProt or InterPro

Protein Sequence (472 amino acids)

>AMB_RS22605 apolipoprotein N-acyltransferase (Magnetospirillum magneticum AMB-1)
MTLEALAARFQALAGWRRRLSLMGLGIVAASALPPTHVLPVLLIAFPAMAWSLDAATTRR
AAFGAGFWWSTGWFAVGLYWISNALLVDAIRFGWMIPFAVFGLSSLLAAFNGLATLAVHL
MRLGRIARIPALAAALTLSEWQRSWVMTGLPWNPVGSVWDVSLPVLQFGALGGIWGLSLL
TYLVVLAPALLSAPGNRRTVAALTLGLPAALWIGGTLRLAQNPEATVPEIRLRLVQAAVP
QANKWRDDQREAHLRDHIALSRGSGFEAISVMIWPETAVSYFLDLDRLHRQMVAAAVPPG
GLLLTGAPRITPRGVEPFQIWNSLMAVTGSAEIAAIYDKVHLVPFGEYVPMRAILPIDKI
THGSTDFSAGPGPVTLDLPGIPPLAPLICYEAIFPGAFIARDQPRPGWIVNVTNDGWFGL
SSGPHQHLAAARMRSIEEGLPQARAANTGISAVIDPVGRLTALLPTGRAGRP