Protein Info for AMB_RS22510 in Magnetospirillum magneticum AMB-1

Annotation: alanine--glyoxylate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K00830, alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC: 2.6.1.44 2.6.1.45 2.6.1.51] (inferred from 100% identity to mag:amb4448)

Predicted SEED Role

"Serine--pyruvate aminotransferase (EC 2.6.1.51) / L-alanine:glyoxylate aminotransferase (EC 2.6.1.44)" in subsystem Photorespiration (oxidative C2 cycle) or Pyruvate Alanine Serine Interconversions or Serine-glyoxylate cycle (EC 2.6.1.44, EC 2.6.1.51)

MetaCyc Pathways

photorespiration I (7/9 steps found)
glycine biosynthesis III (1/1 steps found)
L-serine biosynthesis II (3/4 steps found)
photorespiration III (6/9 steps found)
photorespiration II (6/10 steps found)
formaldehyde assimilation I (serine pathway) (8/13 steps found)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.45

Use Curated BLAST to search for 2.6.1.44 or 2.6.1.45 or 2.6.1.51

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VYS3 at UniProt or InterPro

Protein Sequence (390 amino acids)

>AMB_RS22510 alanine--glyoxylate aminotransferase family protein (Magnetospirillum magneticum AMB-1)
MPATSFQPPLRILMGPGPSDVHPRVLAAQARPTIGHLDPAFVGMMDELKGLLQAAFRSDN
EMTFAVSGPGSAGMEACFVNLIEPGDTVVVCVNGVFGGRMKENVERCGARAVVVEDAWGT
PVDPAKVEAALKANANVKALAFVHAETSTGVESDAGALCALAHAHGALAIVDTVTSLGGI
PVLVDQWGADAVYSGSQKCLSAPPGLSPVTFSSRAVQALKSRKTKVQSWFLDLTLLTAYW
GGGAKRTYHHTAPVNALYGLHESLVMLHEEGLDAAWSRHRAMHEALKAGLEAMGLGLLVA
EQSRLPQLNAVTVPEGVDEAAVRAQLLARFGLEIGAGLGALAGKVWRIGLMGQSATPRHV
MACLTALESVLGEKVKPGAGPAAASRALFG