Protein Info for AMB_RS22350 in Magnetospirillum magneticum AMB-1

Annotation: transcription elongation factor GreB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 TIGR01461: transcription elongation factor GreB" amino acids 27 to 180 (154 residues), 205.3 bits, see alignment E=2.2e-65 PF03449: GreA_GreB_N" amino acids 29 to 98 (70 residues), 79.7 bits, see alignment E=1.5e-26 PF01272: GreA_GreB" amino acids 107 to 180 (74 residues), 86.2 bits, see alignment E=1.2e-28

Best Hits

Swiss-Prot: 62% identical to GREB_NEIMA: Transcription elongation factor GreB (greB) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K04760, transcription elongation factor GreB (inferred from 100% identity to mag:amb4418)

Predicted SEED Role

"Transcription elongation factor GreB" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VYV3 at UniProt or InterPro

Protein Sequence (182 amino acids)

>AMB_RS22350 transcription elongation factor GreB (Magnetospirillum magneticum AMB-1)
MSKAFTKESDGDEDSEDLPQGLPPGAKNYMRPQGFAALKAELSHLHKIERPKVVEVVSWA
AGNGDRSENGDYLYGKKRLREIDRRIRFLTKRMESAHVVDPEQQKKRDQIFFGATVTYAN
ARDEEITVTIVGIDEADLEKGLISWISPVARALLKAAEGDSVPVRTPSGVEMIEVVAISY
GE