Protein Info for AMB_RS21970 in Magnetospirillum magneticum AMB-1

Annotation: molecular chaperone HtpG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 PF13589: HATPase_c_3" amino acids 65 to 147 (83 residues), 38.5 bits, see alignment E=1.1e-13 PF00183: HSP90" amino acids 208 to 621 (414 residues), 407.6 bits, see alignment E=1e-125

Best Hits

Swiss-Prot: 100% identical to HTPG_MAGSA: Chaperone protein HtpG (htpG) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K04079, molecular chaperone HtpG (inferred from 100% identity to mag:amb4343)

MetaCyc: 52% identical to chaperone protein HtpG (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Chaperone protein HtpG" in subsystem Protein chaperones

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VZ28 at UniProt or InterPro

Protein Sequence (623 amino acids)

>AMB_RS21970 molecular chaperone HtpG (Magnetospirillum magneticum AMB-1)
MAEEKRQFQAEVGKLLDIVVHSLYSNKEIFLRELISNASDSCDRLRYGAITEPDLLDGDS
EFRIRLVPDKDAGTLTIIDNGQGMSHDELIANLGTIAKSGTSEFLARLTGDAKKDVSLIG
QFGVGFYSAFMVAEEVTVTSRKAGEAKGWKWVSDGKGEFTVSPAEDAARGAAITLKLREG
ETEFLDAFRLKSIVKRYSDHIAIPVTLKDADKDEETINSASALWTRSKSEITPEQYKEFY
HHVAHAFDEPWSTLHYKAEGAIEYTGLLFIPSSKPLDIFHPDRKQHVKLYVRRVFITDDC
EELLPPYLRFVRGVVDSQDLPLNVSREMLQHNPVLSKIRTGLVKRILGELKKKSEDAEGK
YDEFWAAFGPVLKEGIYEDFERKTDILELCRFRSTHGDGLTTLADYVARMKDGQDAIYTI
TGDDLDQLKKSPQLEGFAAKGVEVLLLTDPIDEFWVSAVRSYAEKDFRSVAAAGADLSKV
KAPEGAEDKKADEAPADELTTLIEAVKLALGERVKDVRPSERLTESAVCLVAAEGEMSMH
LEKMLRAHNQAPGERARILEINPRHALIKGLAARVKAGGTDAGLEDAAFLLLDQARIIEG
EPPADPAAFARRMVSVMEKGLLG