Protein Info for AMB_RS21235 in Magnetospirillum magneticum AMB-1

Annotation: heme transporter HemC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details PF01578: Cytochrom_C_asm" amino acids 18 to 180 (163 residues), 137.1 bits, see alignment E=3.5e-44 TIGR01191: heme exporter protein CcmC" amino acids 41 to 224 (184 residues), 270.7 bits, see alignment E=3.3e-85

Best Hits

Swiss-Prot: 57% identical to CCMC_BRADU: Heme exporter protein C (cycZ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02195, heme exporter protein C (inferred from 100% identity to mag:amb4197)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VZH4 at UniProt or InterPro

Protein Sequence (244 amino acids)

>AMB_RS21235 heme transporter HemC (Magnetospirillum magneticum AMB-1)
MHRFANPARFLRLAKVILPWSNAVAILCLGAGLYFSLFASPADYQQGESVRIMYVHVPSA
WMGMFCYVAMAVFSAMALIWKHPLADLLAKATAPVGAAFTFLCLLTGSLWGKPMWGTWWA
WDARLTSMLILLFLYLGYMALVNAFDDPERGHKAAAILALVGAVNVPVIKWSVDWWNTLH
QPASVVKMGGPAIDGSMLVPLLLMAVGFKAYWISILILRGRAEIASQKIRVIRMAQIHAA
SQGE