Protein Info for AMB_RS20830 in Magnetospirillum magneticum AMB-1

Annotation: peptide-methionine (R)-S-oxide reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00357: methionine-R-sulfoxide reductase
  • amino acids 13 to 134 (122 residues), 187 bits, E=7.3e-60
• PF01641: SelR
  • amino acids 17 to 135 (119 residues), 183.3 bits, E=7.3e-59

Best Hits

Swiss-Prot: 66% identical to MSRB_BRADU: Peptide methionine sulfoxide reductase MsrB (msrB) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K07305, peptide-methionine (R)-S-oxide reductase [EC: 1.8.4.12] (inferred from 100% identity to mag:amb4119)

MetaCyc: 50% identical to methionine sulfoxide reductase B (Escherichia coli K-12 substr. MG1655)
L-methionine (R)-S-oxide reductase. [EC: 1.8.4.14]; Peptide-methionine (R)-S-oxide reductase. [EC: 1.8.4.14, 1.8.4.12]

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12)" (EC 1.8.4.12)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.12 or 1.8.4.14

Sequence Analysis Tools

See Q2VZQ2 at UniProt or InterPro

Protein Sequence (137 amino acids)

>AMB_RS20830 peptide-methionine (R)-S-oxide reductase (Magnetospirillum magneticum AMB-1)
MTGMVTMTDKVVKTEAEWQAQLSPGQYAVTRQKATERPFSGQYDHHFQPGKYACVCCGQE
LFLSEAKFNSGCGWPAFSMPAAPQAVTEERDRSHGMIRTEVLCSRCDAHLGHVFDDGPGP
TGLRYCINSLSLKFEAP