Protein Info for AMB_RS20530 in Magnetospirillum magneticum AMB-1

Annotation: ATP-dependent helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 PF00270: DEAD" amino acids 23 to 190 (168 residues), 149.4 bits, see alignment E=1.2e-47 PF00271: Helicase_C" amino acids 235 to 338 (104 residues), 88.2 bits, see alignment E=6.8e-29 PF03880: DbpA" amino acids 470 to 538 (69 residues), 58.1 bits, see alignment E=1.1e-19

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to mag:amb4061)

Predicted SEED Role

"ATP-dependent RNA helicase"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2VZW0 at UniProt or InterPro

Protein Sequence (586 amino acids)

>AMB_RS20530 ATP-dependent helicase (Magnetospirillum magneticum AMB-1)
MDFFPAGHPLLKALTERDYTDPTAVQEAVLEPGAAGRDLLVSAQTGSGKTVAYGLAIADT
LLGDAFVLEPAAEPLALIVAPTRELALQVHRELTWLYEHAGARVVSCVGGMDPRAEQRML
GQGAHIVVGTPGRLRDHLERGGLRINRLKAVVLDEADEMLDLGFREDLEFILEATPQERR
TLLFSATLPHGIVAMAKRYQRNAWRIAVSAGTQGHADIEYRAVRVAPNEIEHAVVNLLRY
FESPTAMVFCNTRDSVRHLQAILLERGFAAVALSGELGQNERNNALQALRDGRARVCVAT
DVAARGIDLPNLGLVIHAELPQNAQTLQHRSGRTGRAGKKGVSVLLVLLSRRRKADMLLQ
TAGVQAIWSGAPSAEDIRKLDQERLLTSPLLSEENTEDDLAMAKALLAERPAEDIAAALV
RMYRSHLPAAEEVFDPGPGNPSREPREHREREPRPPREGKGPGLPGGSVWFRMNIGRQKN
ADPRWLIPMICRQGKVTKAEIGAIRIFERETRFEIDAGHADRFATALRQIEKAEVRIERL
AEHAAEPAAAARPDDRPRPPAGVKPMGPKKAPWKDKKDGHRKGKPA