Protein Info for AMB_RS20345 in Magnetospirillum magneticum AMB-1

Annotation: 7-cyano-7-deazaguanine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00733: Asn_synthase" amino acids 3 to 60 (58 residues), 31.5 bits, see alignment E=1.5e-11 TIGR00364: queuosine biosynthesis protein QueC" amino acids 4 to 210 (207 residues), 205.1 bits, see alignment E=4.1e-65 PF06508: QueC" amino acids 4 to 217 (214 residues), 249.6 bits, see alignment E=2.3e-78

Best Hits

Swiss-Prot: 100% identical to QUEC_MAGSA: 7-cyano-7-deazaguanine synthase (queC) from Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)

KEGG orthology group: K06920, queuosine biosynthesis protein QueC (inferred from 100% identity to mag:amb4021)

Predicted SEED Role

"Queuosine Biosynthesis QueC ATPase" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W000 at UniProt or InterPro

Protein Sequence (227 amino acids)

>AMB_RS20345 7-cyano-7-deazaguanine synthase (Magnetospirillum magneticum AMB-1)
MKPAIVLLSGGLDSATVLAIAKAEGFAPAALTFRYGQRHAVEIRAAERVAAALGIRDHRI
ADIDLRVFGGSALTSDIAVPKGELDEAIPAGIPVTYVPARNTIMLSFALAFAEVLGAADI
FVGVNAVDYSGYPDCRPDYIKAFEAMANLATKAAVEGTRLTIHTPLIDLTKGQIIRRGLD
LGVDYSITSTCYDPTPDGKACGHCDSCRLRLKGFAEAGLADPAEYAS