Protein Info for AMB_RS19635 in Magnetospirillum magneticum AMB-1

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 PF00072: Response_reg" amino acids 8 to 120 (113 residues), 86.6 bits, see alignment E=2e-28 TIGR00229: PAS domain S-box protein" amino acids 148 to 275 (128 residues), 58.9 bits, see alignment E=2.7e-20 PF00512: HisKA" amino acids 289 to 354 (66 residues), 44.4 bits, see alignment E=2.1e-15 PF02518: HATPase_c" amino acids 401 to 509 (109 residues), 89.7 bits, see alignment E=2.6e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3881)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0E0 at UniProt or InterPro

Protein Sequence (514 amino acids)

>AMB_RS19635 hybrid sensor histidine kinase/response regulator (Magnetospirillum magneticum AMB-1)
MTATRPKILIVDDTQANLLALRKILNKLHVEVIEAASGNDALIHCLEHDFALALLDVNMP
GMDGYELAELMRGEPRTAQVPIIFVTAAYSDDVHRHRGYDVGAVEYIQKPIDDFVLRSKV
RVFLDLYTSRRALEIELARSTAMTQVLRESEARLRHAVSEAPIPIMIHAEDGAVVLLSRV
WCELTGYTPEDIPTVRDWAVRAYGDRGEEIAERIKRHYGMEGARAEGEHEVITATGDVRV
WDFRSAPIEALPDGRRLVISMAVDVTDRHRVQEELAGKTAELERSNADLEQFAYVASHDL
REPLRMVNSFLGLLDKKFGAGLPDDAREYIGYARDGAKRMDSLILDLLEYSRIGRKPPPD
QPIDMRMALDTALSNLTVAVEESGATINTPDSLPALCVDSGEFVRLFQNLIGNAIKYRSP
ERAPVVSLSTRLKGNAWEFRIADNGIGIEPQYFDRVFQIFQRLHSRVEAAGTGIGLAICK
RVVTRYRGRIWVESVPGEGSTFCFTIPVAKPATS