Protein Info for AMB_RS19225 in Magnetospirillum magneticum AMB-1

Annotation: molybdopterin molybdenumtransferase MoeA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 305 to 316 (12 residues), see Phobius details PF03453: MoeA_N" amino acids 12 to 172 (161 residues), 150.6 bits, see alignment E=4.8e-48 TIGR00177: molybdenum cofactor synthesis domain" amino acids 182 to 318 (137 residues), 87.5 bits, see alignment E=4.2e-29 PF00994: MoCF_biosynth" amino acids 185 to 320 (136 residues), 99.4 bits, see alignment E=2.4e-32 PF03454: MoeA_C" amino acids 336 to 404 (69 residues), 69.9 bits, see alignment E=2.7e-23

Best Hits

Swiss-Prot: 41% identical to MOEA_ECOLI: Molybdopterin molybdenumtransferase (moeA) from Escherichia coli (strain K12)

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 100% identity to mag:amb3797)

MetaCyc: 41% identical to molybdopterin molybdotransferase (Escherichia coli K-12 substr. MG1655)
RXN-8348 [EC: 2.10.1.1]

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.10.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W0M4 at UniProt or InterPro

Protein Sequence (411 amino acids)

>AMB_RS19225 molybdopterin molybdenumtransferase MoeA (Magnetospirillum magneticum AMB-1)
MSDRFAVSADMMTVAEALARLEERLAPAVGVEDIRLHDGLGRILADDVVSAVNVPPHDNS
AVDGWAFRRADLPADGILPVVGRVAAGHPLDGPLPAGGAVRIFTGAPMPDGADTVAMQED
CKDLDGRVALPVRLAEGDNARQAGEDISKGSVVLRAGTRLRPQELGVAAATGRSSLKVYR
PLRAAVFSTGDEIRDPGADLPPGCIYDTNRFTATGLLRALGAEVTDLGILPDRFETIRDA
LAEAAVSHQLILTSGGVSVGDEDHVKPAVLAQGSLDFWRLAIKPGRPVALGEVAGTPFVG
LPGNPVAVMVTFMLIARPMVLRLMGAAQTALPRYPVEAGFAFKHKPGRREYLRARLAHMD
GRLVAAKFPSDGSGVLTSMTWSDGLVDIPEDRGDIAPGEMVDFLSYADMMR