Protein Info for AMB_RS18355 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain S-box protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details PF00989: PAS" amino acids 68 to 169 (102 residues), 37.7 bits, see alignment E=6.7e-13 TIGR00229: PAS domain S-box protein" amino acids 68 to 185 (118 residues), 63.3 bits, see alignment E=1.2e-21 amino acids 189 to 308 (120 residues), 29.8 bits, see alignment E=2.8e-11 PF13188: PAS_8" amino acids 70 to 116 (47 residues), 21.7 bits, see alignment 5.1e-08 amino acids 194 to 253 (60 residues), 22.1 bits, see alignment 3.9e-08 PF08448: PAS_4" amino acids 74 to 183 (110 residues), 25 bits, see alignment E=6.4e-09 amino acids 199 to 302 (104 residues), 59.1 bits, see alignment E=1.7e-19 PF13426: PAS_9" amino acids 81 to 167 (87 residues), 31.6 bits, see alignment E=6.1e-11 amino acids 204 to 301 (98 residues), 22.6 bits, see alignment E=3.7e-08 PF08447: PAS_3" amino acids 92 to 174 (83 residues), 36.8 bits, see alignment E=1.4e-12 PF00512: HisKA" amino acids 323 to 388 (66 residues), 48.3 bits, see alignment E=3e-16 PF02518: HATPase_c" amino acids 434 to 545 (112 residues), 98.9 bits, see alignment E=8.9e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3626)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W145 at UniProt or InterPro

Protein Sequence (548 amino acids)

>AMB_RS18355 PAS domain S-box protein (Magnetospirillum magneticum AMB-1)
MLGPIREFVSLEGGFALYYVLAGLGYVAILIALMLVDSDRLAAVLGEEVSRQAEALETQV
ERQVQAREDLRAILDNMPDIFYRTDTEGRLLMVSRSVEGLLGYTVEEVLGLDSAFFHGSD
DSRPQLVAALEAAGGSIIDYELRLRHKDGRILWASTSSRFYLDAQGRRGGTEGVVRLIEE
RKRTELYIRENQALIQAMLDASSDAIMLFRPDGTLLAVNEVMAARFGRRATELTGSCLWD
MFPPDVAKAREEAVTRVVQTGEAIHYLDRRGDLYLDNSIYPVPGVDGVPDKVAVYSRDIT
AQTLAEQKVATYLAELERSNAELEQFAYVASHDLREPLRMISSYLSLLERRYAPKLEGDG
LEFLAFARDGAQRMDRLVLDLLDFSRIQRKGSPIVAMDADPLLHQALRHLAPAIEESGGA
VEVAEGGEAVRVMGDPDQVIRLFQNLIGNAVKYRAPDRAPLVKVSWQRTGGEWECVVADN
GIGIDPQYFERIFGIFQRLHTPDAYAGTGIGLAICKKIVERHGGRIWVESVPDQGSVFHF
TLPAAQPT