Protein Info for AMB_RS18035 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 transmembrane" amino acids 17 to 37 (21 residues), see Phobius details amino acids 291 to 312 (22 residues), see Phobius details PF02743: dCache_1" amino acids 43 to 233 (191 residues), 68.3 bits, see alignment E=2.5e-22 TIGR00229: PAS domain S-box protein" amino acids 320 to 440 (121 residues), 58.5 bits, see alignment E=3.7e-20 PF00989: PAS" amino acids 324 to 435 (112 residues), 31.7 bits, see alignment E=4.8e-11 PF08448: PAS_4" amino acids 332 to 437 (106 residues), 46.3 bits, see alignment E=1.6e-15 PF13426: PAS_9" amino acids 340 to 437 (98 residues), 29.5 bits, see alignment E=2.7e-10 PF08447: PAS_3" amino acids 347 to 429 (83 residues), 36.3 bits, see alignment E=1.9e-12 PF00512: HisKA" amino acids 459 to 523 (65 residues), 43.8 bits, see alignment E=7.8e-15 PF02518: HATPase_c" amino acids 573 to 677 (105 residues), 106.2 bits, see alignment E=4.7e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3564)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W1A7 at UniProt or InterPro

Protein Sequence (681 amino acids)

>AMB_RS18035 PAS domain-containing sensor histidine kinase (Magnetospirillum magneticum AMB-1)
MPSGHKSSPLAGLRPRGIWGLSVSLTLLLIILTGIQLQTGYRRTIQTASANLADTARVTE
EQVRGSLRVVRLMLRAIAEAPRDDTNALRRFMATRTRIVPEIRQAFIVNADGIVTIATLP
QVEGRDTSERSFFRNARELPPARDLFVSEPLPIGQNNSLVIMVSMPLSGPDGQFDGIVAV
SLELGYFQTLLQSVHSGEEGAGALLVTPEGDIIDRDPEPELYVGKNIAKGGAFSMHRKAG
GTANTFVHVTATDGKEKVSAVRSLSEPALPPLVVIVGRPLDGVLAPWRAEALTMAAVVGT
LVIAILGLTALLNRHLVALRASEERYRGLIETQNDLVVRLTPDDRLVFVNEAFARSHGLD
AAQAVGRSWRTFVHEEDQPATAQALATALSPPAFRATVECRMTMTCGLRWVSWEGAAIRD
MSGNIVEIQAAGRDITEWVEHRDRQAELLRNLDKSNRELEQFAYVASHDLREPLRMISSY
LGLLGRRYTALLDEDGRQFMEFARDGAKRMDQMVLDLLEFSRVGRLRDGLGTVSLGEAAS
IAILNLALPIKESGGTVTVAPDLPEITGARGEMIRLMQNLIGNAVKYRQPGRPLTVTVSA
ERNHDGWTLTVADNGIGIPPDGFERIFDIFQRLHSRADYEGTGIGLAVCRKIVEHHGGRI
WVESVPGEGSRFRFTLPGGQA