Protein Info for AMB_RS17540 in Magnetospirillum magneticum AMB-1

Annotation: potassium transporter KefB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 565 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 34 to 51 (18 residues), see Phobius details amino acids 64 to 82 (19 residues), see Phobius details amino acids 92 to 114 (23 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 220 to 238 (19 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details amino acids 274 to 294 (21 residues), see Phobius details amino acids 300 to 320 (21 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 364 to 382 (19 residues), see Phobius details TIGR00932: transporter, monovalent cation:proton antiporter-2 (CPA2) family" amino acids 19 to 290 (272 residues), 263.2 bits, see alignment E=1.5e-82 PF00999: Na_H_Exchanger" amino acids 21 to 378 (358 residues), 212.8 bits, see alignment E=7.1e-67 PF02254: TrkA_N" amino acids 410 to 523 (114 residues), 85.1 bits, see alignment E=4.5e-28

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 100% identity to mag:amb3466)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system protein KefB" in subsystem Glutathione-regulated potassium-efflux system and associated functions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W1K5 at UniProt or InterPro

Protein Sequence (565 amino acids)

>AMB_RS17540 potassium transporter KefB (Magnetospirillum magneticum AMB-1)
MGSDRVHGSEALFDVLSLLLAAVVLVPLFQRFGIPSVLAYLAAGVALGPYTPGPVVDLEV
TRPLAEFGVVFLLFAIGMELPLSRLRTMRRYILGLGLAQVVVTALAIGGISHALGLGSSA
ALIIGLTLAFSSTATVLAILVERGEAVDHHGRIAVAVLIFQDLAVVPVLVLLPLLAGQER
HMAEALALAGGKVALVMAAIFVVGRFLLRPVYRFIATARNPEVFTAANLLLVLAVAWVTG
EAGMSMALGAFLAGLLLADSRYRHQVEADIEPFRGLLLGLFFMTVGMSINLPLVADRLGL
VLGLTLGTVAVKAVVLIGLCRLMKVGLADGLRVGFLLAQGGEFAFVVFGRALELKLLDGG
LGQSLLASVALSMLLTPALAALGRRWSQGLAPQASGEPIPETARHLADHVIIAGYGRVGR
AIGRLLAEHGISFIALDMDVDRVAKAREDGIPVYYGDAGRTGILRSVGIDRARAAVITVN
EARQAERAIGCIRQAAPHLPIVARARDRAQEQLLGDIGATAVIPETVEASLQMAGAVLRS
AGIDEDAVERSLKGYRRRRYGRATE