Protein Info for AMB_RS17390 in Magnetospirillum magneticum AMB-1

Annotation: two-component system response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF00072: Response_reg" amino acids 4 to 115 (112 residues), 97.5 bits, see alignment E=8.1e-32 PF13487: HD_5" amino acids 141 to 305 (165 residues), 123.7 bits, see alignment E=1.1e-39 PF01966: HD" amino acids 153 to 274 (122 residues), 76.8 bits, see alignment E=2.5e-25

Best Hits

Swiss-Prot: 48% identical to RPFG_XANC8: Cyclic di-GMP phosphodiesterase response regulator RpfG (rpfG) from Xanthomonas campestris pv. campestris (strain 8004)

KEGG orthology group: K07814, putative two-component system response regulator (inferred from 100% identity to mag:amb3439)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W1N2 at UniProt or InterPro

Protein Sequence (339 amino acids)

>AMB_RS17390 two-component system response regulator (Magnetospirillum magneticum AMB-1)
MIALLIDDNPTNLMLLKHRLIKIEGCEVVCMESALDALAWCEANTPDIILTDYMMPGMDG
LDFIRQVRRREEMQDVPVVVVTTSDVKEIRQQALDLGAADFLTKPVDGPELMARTRNLLA
LRQSRLALHDRAAEELVMRLSKAAEYRDPETGAHIERMARYSALIARRMGLPNEAVERLE
LAAPMHDVGKVGIPDMILLKPDRLSETEFTIMKQHAMYGWEILKDSSSQLVRLAALIART
HHEKFDGSGYPEGLAGDKIPLEGRIVAVADVFDALTSTRPYKTPWPVDKAAAFLGEQKGC
HFDPACVDAFLSDLGEVLRIKAQFLDHGDEAPPHPLADY