Protein Info for AMB_RS17035 in Magnetospirillum magneticum AMB-1
Annotation: dissimilatory-type sulfite reductase subunit alpha
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 63% identical to DSRA_ALLVD: Sulfite reductase, dissimilatory-type subunit alpha (dsrA) from Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)
KEGG orthology group: K11180, sulfite reductase, dissimilatory-type alpha subunit [EC: 1.8.99.3] (inferred from 100% identity to mag:amb3367)MetaCyc: 63% identical to siroheme sulfite reductase, alpha subunit (Allochromatium vinosum)
1.8.1.g [EC: 1.8.1.g]
Predicted SEED Role
"Dissimilatory sulfite reductase, alpha subunit (EC 1.8.99.3)" (EC 1.8.99.3)
MetaCyc Pathways
- sulfur oxidation IV (intracellular sulfur) (5/7 steps found)
- dissimilatory sulfate reduction I (to hydrogen sufide)) (3/5 steps found)
- superpathway of sulfide oxidation (phototrophic sulfur bacteria) (8/12 steps found)
- superpathway of tetrathionate reduction (Salmonella typhimurium) (2/4 steps found)
- superpathway of thiosulfate metabolism (Desulfovibrio sulfodismutans) (3/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.8.99.3
Use Curated BLAST to search for 1.8.1.g or 1.8.99.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2W1V4 at UniProt or InterPro
Protein Sequence (416 amino acids)
>AMB_RS17035 dissimilatory-type sulfite reductase subunit alpha (Magnetospirillum magneticum AMB-1) MSKKMPPTPMLDQLESGPWPSFVTGLKRLAEDGDKPSAKIMKGLLGQLEHSYQTRKGYWK GGTVGVFGYGAGVIARFSEQAAQFPESSEFHTLRIMPAPGFFYDTKTLRQMCDIWEEHGS GLIALHGQSGDIMFQGCRTEQVQPAWDKLNEMGFDMGGAGAGVRTAASCVGPARCEQACY DTLAAHRAIINDFTDDIHRPSLPYKMKFKFSGCANDCANATQRADVAILGTWKDDMQVDQ DEVKAKVKQLGRKEFINQVIRMCPTQALGLNDDDTLDVDNKSCVRCMHCINVCTKALKPG KERGICILVGGKRTLKIGDLMGTVLVPFMKLETEEDFAGLVELAHNMLDFFADNALEHER TGEMIERIGLVNYLEGLGLELDVNMINQPRTNSYIRTDGWDEEARKWAERKNSAAE