Protein Info for AMB_RS16315 in Magnetospirillum magneticum AMB-1
Annotation: acyl-CoA dehydrogenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 67% identical to GCDH_BOVIN: Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) from Bos taurus
KEGG orthology group: K00252, glutaryl-CoA dehydrogenase [EC: 1.3.99.7] (inferred from 100% identity to mag:amb3231)MetaCyc: 70% identical to glutaryl-CoA dehydrogenase (Pseudomonas putida KT2440)
GLUTARYL-COA-DEHYDROGENASE-RXN [EC: 1.3.8.6]
Predicted SEED Role
"Glutaryl-CoA dehydrogenase (EC 1.3.99.7)" (EC 1.3.99.7)
MetaCyc Pathways
- glutaryl-CoA degradation (3/5 steps found)
- benzoate fermentation (to acetate and cyclohexane carboxylate) (7/17 steps found)
- crotonate fermentation (to acetate and cyclohexane carboxylate) (5/16 steps found)
- toluene degradation VI (anaerobic) (6/18 steps found)
- L-tryptophan degradation III (eukaryotic) (3/15 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.3.8.6 or 1.3.99.7
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2W290 at UniProt or InterPro
Protein Sequence (392 amino acids)
>AMB_RS16315 acyl-CoA dehydrogenase (Magnetospirillum magneticum AMB-1) MQHFKWDDPFLLEDQLSEDEKLIRDSAHAYCQEKLQPRVMKAFRDETFDREIMNEMGEMG LLGPTIPEEYGGPGVNHVAYGLISREVERVDSGYRSAMSVQSSLVMHPIFSYGTEEQKKK YLPRLATGEIIGCFGLTEPDAGSDPGGMRTRAKKVDGGYLLTGSKMWITNSPISDIAIVW AKSDAHEGKIKGFIVEKGIKGFTTPKIEGKLSLRASITGEIVLDEAFVPDEALMPNASGL GGPFGCLNKARYGIAWGVIGAAEFCWHAARQYMLDRKQFGRPLAANQIPQLKLANMMTEI TLGLQACVRVGRMMDDHTWAPEAVSLIKRNNCGKALDIARMARDMHGGNGISEEFHVIRH MVNLETVNTYEGAHDVHALILGRAMTGIQAFS