Protein Info for AMB_RS15470 in Magnetospirillum magneticum AMB-1

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 transmembrane" amino acids 123 to 142 (20 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 260 to 271 (12 residues), see Phobius details TIGR02823: putative quinone oxidoreductase, YhdH/YhfP family" amino acids 6 to 328 (323 residues), 433.1 bits, see alignment E=2.6e-134 PF08240: ADH_N" amino acids 30 to 117 (88 residues), 54.3 bits, see alignment E=1.4e-18 PF00107: ADH_zinc_N" amino acids 162 to 275 (114 residues), 40.4 bits, see alignment E=2.8e-14

Best Hits

Swiss-Prot: 61% identical to ACUI_RUEPO: Acrylyl-CoA reductase AcuI (acuI) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

KEGG orthology group: None (inferred from 100% identity to mag:amb3072)

MetaCyc: 61% identical to acryloyl-CoA reductase monomer (Ruegeria pomeroyi DSS-3)
RXN-9087 [EC: 1.3.1.84]

Predicted SEED Role

"YhdH, a putative quinone oxidoreductase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.1.84

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W2P9 at UniProt or InterPro

Protein Sequence (331 amino acids)

>AMB_RS15470 oxidoreductase (Magnetospirillum magneticum AMB-1)
MSDFPALMLDETDGKVTASIRRLTDSDLPEGEVLVKVEYSTLNYKDGMILGGLGRLVRKY
PHVPGVDFAGTVEASASPEFKPGDRVILTGWRVGETHWGGYAAKARVKADWLVPLPQGLS
ARQAMAVGTAGFTAMLAVMALEDHGLRTSDEGEVLVTGAAGGLGSVAVLLLSKLGYRVAA
STGRESLGEYLRSLGASSIVDRAEVGAPPAKPLLSERWAAAVDSVGGATLANTVASLRVR
GAVASCGNAGGVEFNLTVLPFLLRGACILGIDSVMAPKPRRLIAWKRLAELLPLDRLDSL
TTEIRLVDLPEMGAKILKGEVKGRVVVDPNR