Protein Info for AMB_RS15305 in Magnetospirillum magneticum AMB-1

Annotation: adenylate/guanylate cyclase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 583 transmembrane" amino acids 130 to 158 (29 residues), see Phobius details amino acids 171 to 191 (21 residues), see Phobius details PF00211: Guanylate_cyc" amino acids 419 to 573 (155 residues), 45.9 bits, see alignment E=2.7e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb3039)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W2T2 at UniProt or InterPro

Protein Sequence (583 amino acids)

>AMB_RS15305 adenylate/guanylate cyclase domain-containing protein (Magnetospirillum magneticum AMB-1)
MIIVHFEVYVMEGRGWMLHARFPRLERDEAVREAKELESTLGVRTKVLRETYNTDSNVFD
EVEVYLSGHNIQPRKSVAAVGGGGGGGTGGKGGGKDSGKGGAAKAGAARKAAGSARARAN
GPEIGAGAAILRLTVILLVAAGVGLGVLRLVPSAIVILYDFGFRITPDEYGQMLIIVFGL
VFLMTAVPLGLRFMPRNANIQFNNARAAAPPPRPQPSEAVKKSLNKLAKKAEAEMIPETW
GDDPEPEPEPEPPPPPEETPPPQPPPVEEPSAAAAAVDAIPATPAFETTRKVTDRFVDKS
MQVVRQVAPSTDKYTTFGLNLFMAGAVQAIARTQKLDSAGQRKLLKTIIEKLGTPGDLAA
AFYDKVPEYMGEQRYARMFESGKSAMESWAEGDEGTPMIKLQTSLKDWNKPATEKKQPSL
MTVMFTDMVGSTDLTQARGDQAAQEIVRKHNAIVRTALTQFAGREVKHTGDGIMASFASA
ANAVEATVQIQRQVTAHNEKQPNLPLHLRIGLNAGEPIQEEDDLFGSTVQLAARVCAATD
SDQTLCTQVVKDLAGGTGAFTDGGMHALKGFRDKFQLWEVLWR