Protein Info for AMB_RS14750 in Magnetospirillum magneticum AMB-1

Annotation: PAS domain S-box protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1248 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 145 to 160 (16 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 509 to 529 (21 residues), see Phobius details PF00672: HAMP" amino acids 343 to 391 (49 residues), 25.3 bits, see alignment (E = 5.4e-09) PF13185: GAF_2" amino acids 417 to 527 (111 residues), 40.6 bits, see alignment E=1.1e-13 TIGR00229: PAS domain S-box protein" amino acids 591 to 704 (114 residues), 43.1 bits, see alignment E=2.1e-15 PF13426: PAS_9" amino acids 604 to 698 (95 residues), 34 bits, see alignment 1.1e-11 PF08448: PAS_4" amino acids 604 to 700 (97 residues), 25.2 bits, see alignment 5.8e-09 PF00512: HisKA" amino acids 720 to 784 (65 residues), 81.7 bits, see alignment 1.1e-26 PF02518: HATPase_c" amino acids 831 to 945 (115 residues), 97 bits, see alignment E=3.4e-31 PF00072: Response_reg" amino acids 966 to 1080 (115 residues), 66.8 bits, see alignment E=6.4e-22 amino acids 1112 to 1222 (111 residues), 98.1 bits, see alignment E=1.3e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb2930)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W341 at UniProt or InterPro

Protein Sequence (1248 amino acids)

>AMB_RS14750 PAS domain S-box protein (Magnetospirillum magneticum AMB-1)
MRVSTVVSLGMGLVILASMVLIGRVMAPHLDRQASIQSGRAAERLMELGLGAATRISAER
GPANGILGSDLPLPSDRVEALRAAREVTDAALHEVTAELNGRHPLRQSDVIALSLAESGR
QLAAARRQIDTLASRPRAERNDAEVLAAVSAMVEVLPLLAPGLNVIENNLAQADPALINF
VTIARLATEMRDQAGQLGSVFTAPFVARRPMSVDELARIERSLGIIQALDYQLRLALDKT
GSPPELKAALAVIDAEFFGGGLPLARRIRDMGRTGGEYGMGAADFAKIYVPQMNVILGLR
GAALHSISARMTGIEAESRSAMQITLGLAGIVFVSVLGCFLVIVRRMWHPLSQVNRALGQ
LARGEDRMDLPLVRRHDEIGEVVDSLTRLAAVVRERAEESHVSGLVAKITSGLQSAEDLA
SLSQVLFTHLEPILHLGFAGYFRLDDQARALLSCGGYARDGEASPPGRVELGDGLVGECA
LEKREILIADPPPGYVRARTGLLSALPRAVLILPVLSGGQCLGVIELAMLQPLGGTGRRV
LDDVLPLLAMRMEILARTERTQQLLAATRELAETLEANQTEIQSLLSEQQAIFEAATVGI
AFLKNRVIVRGNPRLDKLFGYGPGELVGQSTRIWFADDAAFADVGGAYEALSRGEVHQRE
QEYLRKDQSRFWCRISGSAIDPSDLSRGTVWMLEDVTQARATAEAQARAKDAAEDAARTK
SDFLANMSHEIRTPMNAIIGMAHLALKTDLDPRQKDYVRKIQQSGQHLLGIINDILDFSK
IEAGKLEVEATEIHLDKVLENVGNLISEKATAKGLELLFDVGAGVPLDLMGDALRLGQVL
INYANNAVKFTEAGEIVVAVRLMEDLGPDVMLRFEVRDTGIGLTDEQKARLFQSFSQADT
STTRKFGGTGLGLAISKKLAELMGGSVGVDSVPGQGSTFWFTARLGKGKPRAPLIPEAEL
QGRRMLVVDDNENARAVLVDMLSAMSFEVDAVDSGAKALDAIRDAVLDLPYDVVFLDWQM
PDMDGLEVAEQIHSIRLPFPPHLIMVTAYGREEIIKGAQAADIGEVLIKPVSPAALFDSI
MRVFASDQRRDEAEDVSEGGSVDHAALRGLKVLLVEDNDLNQEVAGEILRDAGIEVEIAD
NGLIAVEKARAGVYDLILMDMQMPVMDGVTATREIRRLGHVDLPIIAMTANAMQADRDKC
LEAGMNDHIAKPIDPDTMFSTISRWCAAEPPRRAGTASDGCATKVDGR